Iodine Nutrition Level Survey Of The Childbearing Age Women In Areas Of Iodine Deficiency Of Jinan

Objective:Investigate iodine deficiency disease(IDD) prevention and control situation of Jinan,then provide a basis to take targeted preventive measures and adjust intervention strategies scientifically.Univeral iodine salt,qualified iodine salt consumption rate,iodine content of drinking water and urinary iodine level of fertile women of each family are examined in iodine deficiency areas in Jinan.Explore the relations between household salt iodine content,iodine content of drinking water and urinary iodine.Evaluate the nutritional standards of iodine in population.Methods:Using stratified random sampling method,288 or 300 household salt samples are collected in each county(city,district) in iodine deficiency areas in Jinan.The first morning urine or urine after 8～12h meat of 15～55fertile women is collected to examine the urine iodine level.If the household does not meet the sampling requirements,the monitoring of iodine salt and urine iodine postponed to their neighbors.Collect every 4 copies of each village and get 144 or 150 urine samples in each county(city,district).Sample surveys of drinking water in each village(neighborhood committee) are taken and 1 water sample is collected in the village with central water supplying.When it comes to the villages without central water supplying,the three most drinking water resources are collected and examined according to the numbers of drinking people.The data is treated with statistical software SPSS13.0.Water iodine,salt iodine and urine iodine are expressed by X±S,the median(M),and urine distribution by sample size(n),%.The units of Water iodine and urine iodine are micrograms per liter(mg/L) and micrograms per kilograms(mg/kg) seperately.Comparison between water iodine,urinary iodine and salt iodine is done by Kruskal-Wallis nonparametric test,and correlation analysis between water iodine and urine iodine by Spearman rank correlation analysis.Single-factor analysis of variance(ANOVA, Post Hoc Tests) and x~2 test are used separately in comparing of measurement data and rate.Significant difference is justed when P is not over 0.05.Results:Household salt iodine content and urinary iodine and the iodine content of drinking water were tested in 8 iodine deficiency Counties(districts) in Jinan.Iodine nutrition staus and related factors were understood.The results show such statistical differences among counties(districts) in Jinan as the rate of qualified iodine salt consumption(x~2=136.53,P＜0.05),non-iodine salt rate(x~2=67.79,P＜0.05),iodine salt covering rate(x~2=67.73,P＜0.05) and qualified rate of iodine salt(x~2= 135.00,P＜0.05).1118 copies of urine iodine of fertile women are detected and the unrine iodine value at 1.59～2946.38ug/L with the median of 118.94ug/L;the median urinary iodine of various counties(districts) is from 97.09 to 154.79ug/L.The difference of urine iodine concentration of various counties(districts) was significant(x~2=83.75,P＜0.05),and that between every two counties(districts) was significant in statistic by multiple comparisons(LSD method)(F=5.92,P＜0.05).3364 household drinking water samples were tested and the result was 0.00～968.29ug/l with the median of 8.77ug/l.There was drinking water samples that water idodine is over 10ug/l in each district.Water Iodine content of each district is different in statistic(x~2=525.88,P＜0.05).The differences of water iodine between Lixia,Shizhong,Huaiyin,Pingyin Changqing and Licheng districts were not significant in statistic by multiple comparisons(LSD method)(P＞0.05).And that between Zhangqiu,Tianqiao and other districts were significant(F=31.82,P＜0.05).Conclusions:1.At municipal level,the iodine nutrition status in Jinan is optimal with appropriate iodine intake.At county level,there are three counties in which iodine nutrition is deficient lightly with inadequate iodine intake.2.The current strategies to prevent and control IDD are correct and effective.Only the utilization of qualified iodine salt is required to further improve.3.Salt iodine content,iodine content of drinking water and urine iodine are positively correlated.