The Clinic Research Of QingGanXiaoYing Prescription For Treatment Of Graves' Ophthalmopathy With Prosperity Of Hepatic Fire

Objective:Treatment with prednisone acetate comparative study of the program,the objective evaluation of traditional Chinese medicine treatment QingGanXiaoYing prescription of the efficacy and safety.Method:Based on simple random,non-blind,controlled clinical trial principles,in line with the 76 cases selected GO diagnosis,as well as the TCM Prosperity of hepatic fire standards in line with the patients,all completed observation.76 cases were randomly divided into two groups,which combines Chinese and Western treatment group(hereinafter referred to as the treatment group)38 cases,the basis of the drug plus side treatment QingGanXiaoYing prescription;Western medicine control group(hereinafter referred to as the control group) 38 cases,the basis of the drug plus acetate prednisone treatment.Courses are for 8 weeks.Result:①The symptoms and signs of improvement:the treatment group improvements in a variety of symptoms and signs are better than the control group,which heads to improve the level of inflation in tears compared to the two groups with significant statistical significance (P＜0.01),finger tremor improved statistical significance compared(P＜0.05),irritability palpitations improvement was statistically significant compared to close to(P=0.09);②exophthalmos,the visual improvement:the treatment group after treatment to improve the situation exophthalmos obviously gifted in the control group,comparison between groups was statistically significant(P＜0.05),the two groups after treatment were significantly improved visual acuity(P＜0.01 or P＜0.05),but inter-group comparison was not significant(P＞0.05);③thyroid hormone and thyroid-associated antibodies to improve the role:the two groups after treatment TT3,TT4,FT3,FT4,were significantly decreased(P＜0.01 or P＜0.05),and TT3,FT3, FT4 decline was better than the control group,but Comparison between groups was not significant(P＞0.05),the two groups after treatment TGAb,TMAb,TRAb were significantly decreased(P＜0.01 or P＜0.05),after treatment,TGAb,TMAb decline significantly better than the control group(P＜0.05);④security:In this study,both of them have good security,no significant difference between the two groups statistically significant.Conclusion:The treatment group in improving the degree of exophthalmos,eye symptoms and clinical symptoms of high metabolic its better than the control group alone;The treatment group may improve in patients with abnormal thyroid function,the thyroid function(TT3,TT4, FT3,FT4) decrease,TSH rise are better than the control group;The treatment group side with abnormal regulation of thyroid-associated antibodies(TRAb,TGAb,TMAb) the role of immune regulatory function,to improve the hyperthyroidism efficacy,shorten the course,reduce the relapse rate in a certain sense;QingGanXiaoYing Prescription security,non-toxic side effects.