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Study Of The Diagnostic Value Of Diffusion-weighted MR Imaging For Residual Tumors After Transarterial Chemoembolization For Primary Hepatocellular Carcinoma

Posted on:2011-07-27Degree:MasterType:Thesis
Country:ChinaCandidate:F DongFull Text:PDF
GTID:2144360305458033Subject:Medical imaging and nuclear medicine
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PURPOSE:This paper was to study the diagnostic value of diffusion-weighted MR imaging for residual tumors of hepatocellular carcinoma after transarterial chemoembolization (TACE).MATERIALS AND METHODS:Between January 2007 and January 2010, a total of 13 hepatocellular carcinoma patients, proved by pathology or clinical evidence, who had undergone TACE in The 2nd Affiliated Hospital of Zhejiang University School of Medicine were studied. For the lesions of interest on CT, MR imaging-including T1-weighted imaging (T1WI), T2-weighted imaging (T2WI), dynamic contrast-enhanced MR imaging, diffusion-weighted imaging (DWI)-were performed. The follow-up lipiodol CT, combined with hepatic arteriography and laboratory examination were regarded as gold standard. The diagnostic accuracy of T1WI, T2WI, dynamic contrast-enhanced and DWI was compared with that of T1WI, T2WI and dynamic contrast-enhanced.RESULTS:The sensitivity, specificity, accuracy for T1WI, T2WI, dynamic contrast-enhanced combined with DWI were 96.2%,91.7%and 95.4%respectively, while the sensitivity, specificity, accuracy for T1WI, T2WI and dynamic contrast-enhanced separately were 79.2%,100%and 83.1%respectively. The statistical difference between the two diagnostic protocols was significant(P<0.05).CONCLUSIONS:DWI has an important diagnostic value for residual tumors of hepatocellular carcinoma after transarterial chemoembolization, especially for those hypovascular tumors, which is an excellent complement for dynamic contrast-enhanced.
Keywords/Search Tags:liver neoplasms, transarterial chemoembolization, MRI, diffusion Magnetic Resonance Imaging, diagnosis
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