| Background Prolapse of lumbar intervertebral disc (PLID) is not be realized in Chinese history.It was not discribed untill Sui Dynasty. The mssage and traction was used to treat it in time of Hippcrates. The first PLID-operation of the world was reported in 1934. The first PLID-operation was reported in 1946 in China. The symptom of the low back of PLID is coincident to liver channeland gallbladder meridian. The qi function of the two meridian channel can be exchanged.And to treat the PLID by the herb meridial distribution of liver channel.The radix bupleuri is meridial disribute to the liver channel, which can dispersing stagnated liver qi for promoting bile flow, and guid the medicine to the liver channel and gallbladder meridian, regulate the emotional. One of the pharmacological actions of it is antiinflammatory and abirritation. Then it come to a conclusion:it could improve the effect of the formulas of Chinese medicine to treat the PLID.Objectives To make a retrospective research to the radix bupleuri's apply in the clinic and summarize the expeirience of it. Then, to objectively assess the clinical effect of the eccentral type of prolapse of lumbar intervertebral disc blood stasis syndrome which be treat by the formulas of Chinese medicine with radix bupleuri, and discuss the effect of the traditional Chinese medicine to the prolapse of lumbar intervertebral disc and the weight of the radix bupleuri in it.Methods Make statistic to the in-patients with PLID in orthopaedic ward 2 of GuangDong Province Hospital Of Traditional Chinese Medicine ZHUHAI BRANCH from January,2007 to May,2010 on file. Statistic analized the result with Statistical Product and Service Solutions (SPSS)16.0 and Microsoft Office Excel 2003, and did it by chi-square test and rank sum test. Make Clustering analysis to the syndrome.To access the clinical effect of 18 qualified in-patients in GuangDong Province Hospital of Traditional Chinese Medicine ZHUHAI BRANCH, and treat them with RCT design, which were devided into to groups by 1:1.They were treated by 3 days of the formulas of Chinese medicine and the combined conservative therapy, by assessment standards questionnaire of treatment results of low back pain disease of Japanese Orthopedic Association (JOA questionnaire), and visual analogue scales (VAS).Statistic analized the result with Statistical Product and Service Solutions (SPSS)16.0 and Microsoft Office Excel 2003,and did it again with the result which were eliminated the influnced cases by the other medicine. Result The course of disease is not statistically significan. (P>0.05) And the number of the case is totally 1373. radix buleuri was appled in 15.22% case (209) plan. There are 173 case with blood stasis-only, while account for 82.8% of the number of case with radix bupleuri. And 36 case with no-blood stasis, while account for 17.22% of the number of case with radix bupleuri. The number of cases mixed with blood stasis is 205, which account for 98.09% of the radix bupleuri-case.The result of the desk study:the treatment group (with radix bupleuri) and control group (without radix bupleuri) is not statistically significant by JOA questionnaire and VAS. (P>0.05) Then statistic by the SPSS (Statistical Product and Service Solutions).While the cases which were influnced by the other medicine were eliminated. The result of the rest of treatment group (with radix bupleuri) and control group (without radix bupleuri) is not statistically significant by JOA questionnaire VAS. (P>0.05)Conclusion The retrospective review shows that the radix bupleuri as assistant is the admitted herb to treat the blood stasis of PLID by clinician. Howerver, the clinical effect of treatment group (with radix bupleuri) and control group (without radix bupleuri) is identical.While the JOA questionnaire and the VAS is probably not assess the herb completely. It need a new scale to do it. |
