The Research Of Syndromes Defined By Traditional Chinese Medicine And Correlation Factor In Vascular Cognitive Impairment No Dementia

Objscreen ingThis research is to screening the patients of Vascular cognitive impairment no dementia(VCIND), investigate the influence factor, explore the cognitive impairment characteristics,to reveal the pattern of syndrome of TCM and the the relative factor of the patients with VCIND. To Provid evidence of etiolog and the thread of prevention and cure for VCIND.MethodsThis topic adopt the mathod of Cross-Sectional Studies. Record the general state of all patients in detail. Use Montreal Cognitive Assessment (MOCA) and clock drawing (CLOX) test to screen all stroke cases. We use these tow kinds of cognitive scales to validate patients with VCIND and patients post stroke without cognitive impairment. For these VCIND patients, we use Hachinski Ischemic Scale(HIS) to excluse the one who's cognitive impairment is not caused by cerebrovascular disease, While use Hamilton Depression Scale(HAMD) to excluse the one have depression post stroke. Then, use the Scale for Differentiation of Syndrome in Vascular Dementia(SDSVD) to acquire VCIND and the control group's syndrome of TCM and their marks.ResultsThis study includes 350 cases of first time stroke patients, we screened 89 cases of VCIND, exclusd 4 cases with depression and 5 cases by HIS, finally, collected 80 patients with VCIND, and 75 cases of control group.Compare the general features and cerebrovascular disease(CVD) characteristics of VCIND patients with the control group, We can see that the older ages(over 70 years old),acute phase of stroke,large-scale damage,Thalamus damage as well as the left hemisphere injury in VCIND were significantly more than the control group.The main cognition impairment of VCIND patients were structural and organizational obstacles as well as delayed memory function impairment. In clock drawing test, the abnormal patients of CLOXI test were in major, illustrate that VCIVD patients with executive dysfunctionIn the seven VCIND syndromes, the most is deficiency of kidney-essence, followed by Blood Stasis, Phlegm Blockage of Orifice, and Qi-Blood Deficiency, Excess of Liver-Yang and Constipation-Turbid Stagnation, Excess of Internal Fire were all few. These syndromes were also common in the control group, with little frequcncy. And the VCIND group had more combined syndromes.ConclusionsThe results show that old age,large-scale damage,acute phase of stroke and left hemisphere lesions as well as the thalamus damages are easier to cause cognitive function.The global cognitive level of VCIND was lower than the control group especially, the structural and organizational obstacles as well as delayed memory impairment was most obviously.In the TCM syndromes of VCIND, the most commen is deficiency of kidney-essence, and the syndromes of VCIND is more complex than the control group. Excess and deficiency would generate in the same patient.