Clinical Research On Acupuncture Treatment For Chronic Pelvic Inflammatory Disease By Regulating Blood-stasis Constitution

ObjectiveTo observe and make a comparison of two groups of patients with chronic pelvic inflammatory disease (CPID) in their symptoms, physical signs, blood-stasis constitution conversion points, blood-stasis quantitative integral and hemorrheology index taken both before and after the treatment. To explore the clinical therapeutic effect of acupuncture treatment on treating CPID by regulating the patients'blood-stasis constitution.MethodsSixty patients with CPID were collected from gynecology department and acupuncture department outpatients room during 3/2009 to 3/2010, all of whom were given a text and diagnosed as blood-stasis constitution. The patients were randomly divided into two groups, with both 30 patients in each group. Patients in Treatment Group were given acupuncture treatment by regulating their constitution. Geshu (BL17), Ganshu (BL18), Shenque (RN8),Sanyinjiao (SP6),Zhongji (RN3),Daimai (GB26) and Ciliao(BL32) were used. Scraping and blood-letting therapy were applied at the first time treatment. Geshu (BL17) and Ganshu (BL18) were acupunctured regularly. Moxibustion on ginger and salt was used on Shenque (RN8). The other acupoints were dealt with Warming Needle Moxibustion. Suitable living habits were suggested to the patients. Patients in Control Group accepted ordinary acupuncture treatment. Sanyinjiao (SP6), Zhongji (RN3), Daimai (GB26) and Ciliao(BL32) were used as main acupoints. Ligou (LR5) and Yinlingquan(SP9) were used additionally for those who were diagnosed as dampness-heat pattern, while for those with Qi-stagnation and blood stasis pattern, Taichong (LR3) and Geshu (BL17) were added. All the acupoints were used only by acupuncture without Moxibustion, and only reduction method were applied. Course of treatment lasted for three months. All the patients were given treatment twice every week, with two days' interval. Treatment was paused when one was in her menstruation. Symptoms, physical signs and blood-stasis quantitative integral were calculated both before and after the whole treatment. Blood rheology indexes were also taken to make a comparison. SPSS 17.0 software package were used to analysis all the data. Gaussian distribution measurement data was recorded by mean±SD(x±s), and analyzed by paired T-test and independent samples T-test. Abnormal distribution measurement data was recorded by median and analyzed by Rank sum test. Numeration data was analyzed by chi-square test (x2 test).ResultsDuring the treatment process,1 case of the treatment group was lost, and 2 of the control group. Therefore, there were 29 patients in the treatment group and 28 cases in the control group at the end of the treatment. 1.Clinic effects:Synthesized effects:total effective rate of treatment group was 89.7%, and it was 69.7% in the control group. There was statistical difference between the two groups (P<0.05). Treatment group had better curative effect than the control group. Symptoms effects:total effective rate were 86.2% in treatment group and 67.9% in control group. The difference was significant (P<0.05), which showed that symptoms of the treatment group improved better than the other group. Physical signs effects:the treatment had a total effective rate of 89.7%, which in the control group was 67.9%. It was a significant difference between the two (P<0.05). 2.Conversion points of Blood-stasis Constitution itemsAfter the treatment, conversion points decreased significantly in the treatment group, compared with those before the treatment (P<0.05). But no statistical difference occurred in the control group (P>0.05) Conversion points of the two groups were compared by SPSS, and there was significant difference between them (P<0.05), which meant that the constitution-regulating treatment made patients'constitution improved. 3.Blood-stasis quantitative integrals:There was a statistical difference within the treatment group itself (P<0.05), compared the integrals before and after the treatment. But no statistical difference within the control group (P＞0.05). The treatment group decreased significantly larger than the control group in the blood-stasis quantitative integrals, suggesting the constitution-regulating treatment improved blood-stasis condition better than the traditional acupuncture treatment. 4.Hemorheological indexesAll the hemorrheology relevant comparison testing except HCT were significantly different (P<0.05) in the treatment group. Whole blood viscosity were significantly changed compared with those before treatment (P<0.05), but HCT and PV were tested without any statistical difference in the control group (P>0.05). Inter-group comparison after treatment were significantly different, which reveled that hemorheological changes were greater in the treatment groupConclusionBoth the treatment and the control group got satisfying therapeutic effects, but the treatment group worked better in improving symptoms, physical signs and the blood-stasis condition of the CPID patients, so as the hemorheological changes. Accordingly, the constitution-regulating therapy reacted on the patients'hemorheological changes so that to improve symptoms and physical signs. Blood-stasis constitution-regulating therapy was an effective, safe therapy to cure CPID.