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Intestinal Fecal Flora Analysis Of Mongolian Ulcerative Colitis Patients In Chifeng

Posted on:2011-04-01Degree:MasterType:Thesis
Country:ChinaCandidate:C Y LuoFull Text:PDF
GTID:2144360305475898Subject:Biochemistry and Molecular Biology
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Objective:Studying the alteration of intestinal flor in active ulcerative colitis, ulcerative colitis in remission patinents and the change of pathology for Mongolian in Chifeng region.To explor the relationship between the change of ulcerative colitis (UC)intestinal flora and occurrence and development of disease. To provide the basis for clinical treatment of UC.Methods:Case collection and analysis method of Fecal Flora1.Collecting 32 cases Mongolian (UC) Ulcerative Colitis patients who were treated from two third level hospitals from October 2008 to December 2009, in accordance with Sourtherland DAI,individed into two groups,UC active and UC remission.2.Choosing 18 Mongolian cases of physical examination from our hospital as control group.3.Collecting excrement of the cases and control groups for Enterobacteria,Enterococcus,Staphylococcus, Yeast,Bacteroides,bifidobacte rium,peptococcus,lactobacillus, eubacterium and Clostridium,above 10 kinds of intestinal predominant flor make quantitative analysis of the flora.Results1. Comparing with the control group, the quantity of Enterobacteria (9.00±0.19, p<0.01) in the Intestinal Flora with active (UC) Ulcerative Colitis patients, Enterococcus (8.04±0.38, p<0.01) increases obviously,the quantity of fusiformis (6.83±0.34, p<0.05) increase slightly,the quantity of Bacillus Bifidus (7.34±0.29, p<0.01) decrease obviously and other Bacteriums do not change obviously.2. Enterobacteria (8.54±0.24, P<0.05) in remission (UC) Ulcerative Colitis patinents is the trend of increasment, the quantity of Bacillus Bifidus and Eubacterium decrease slightly,but it is not obvious difference. Other Bacterias do not change obviously.Conclusions1, The Mongolian Ulcerative Coliti patients of ChiFeng exist flora imblanceIn different degrees.,2, the different stages (UC) Ulcerative Colitis patinents, it has the relevant connections between the UC patients with changes in intestinal predominant flora and the activity of UC.
Keywords/Search Tags:Ulcerative colitis, Flora analysis, Beneficial bacteria
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