Imaging Features And Surgical Treatment Of Malignant Pancreatic Neuroendocrine Tumor

Imaging features and surgical treatment of malignant pancreatic neuroendocrine tumorObjective:To investigate the imaging methods and surgical options for the malignant pancreatic neuroendocrine tumor.Methods:We retrospectively summarized the clinic data of 32 patients with malignant pancreatic neuroendocrine tumors who admitted in PeKing Union Medical College Hospital between 2003.1 and 2009.12. All patients underwent BUS, CT examination, or further endoscopic ultrasound, PET, somatostatin receptor imaging, etc. The surgical methods were selected according to locatin of tumors and disease characteristics. The general information, postoperative pathology results, prognosis, imaging methods and surgical options were also collected.Results:The functional neuroendocrine tumors induced clinical endocrine syndrome of all patients and the clinical symptoms of non-functional neuroendocrine tumors were eased or partial remissioned after pancreatic resection. The endocrine-induced clinical syndrome of functional pancreatic neuroendocrine tumors metastasised in liver can be reduced by cytoreductive surgery.Conclusion:Malignant pancreatic neuroendocrine tumors should be actively treated surgically. Liver metastases resection combined with embolization or radiofrequency ablation can relieve clinic symptoms, so that patients can get clinical benefit.