The Application Of Narrow Band-imaging In Early Esophageal Cancer And Premalignant Lesions

Objective:To study the value of the endoscopic narrow band imaging technique in distinguish the early esophageal cancer and premalignant lesions .Method: Use normal endoscopy and narrow band imaging respectively to observe the minimal changes of esophagus, such as early esophageal cancer and precancerous lesions, by comparing the lesions of the definition and boundary, then use the NBI + Magnifying endoscope to observe the intraepithelial papillary capillary loop(IPCL) in the lesions and decide the type of them ,and also biopsy in the area where the IPCL obviously changed ,then study the relationship between the classification of IPCL and the pathology .Results: (1) To focus on the boundary of NBI display boundaries clear up to 97.8%, normal endoscopy is 33.3%,the P<0.05 is statistic,(2) About the IPCL :All the early esophageal cancer have the grade of III and the above changed ,and the main is the IV grade changed 83.3%(5/6),the high grade intraepithelial neoplasia have the grade of III-IV changed, and the main is the III grade changed77.8%(14/18),the low grade intraepithelial neoplasia have the grade of II-III changed81.8%(9/11),(3)With the rise of IPCL typing its pathological malignancy also increased, the III-IV-level of IPCL typing hint pathological changes have mainly the high grade intraepithelial neoplasia and the above.Conclusion:To compare with the normal endoscopy ,NBI improve the recognition of the digestive musical and can enhance in recognizing the mile pathological changes ,and improve the relevance ratio of the lesions . by observing the type of IPCL , NBI + Magnifying endoscope can improve the coincidence of high grade intraepithelial neoplasia and early esophageal cancer with pathology ,can improve the diagnosis of the kind of lesions in the endoscopy .so NBI is valuable in recognizing the early esophageal cancer and the precancerous lesion.