Clinical Research Of Fine Melt Capsule Treat Early Cirrhosis

Objective:As the early cirrhosis patients for research object, Observes fine melt capsule to it clinical curative effect's affection, Reveals it stable liver function, Resists liver fiber melt and Delays cirrhosis of the liver tenor's mechanism, in order to provide reliable clinical application basis.Methods:63 the early cirrhosis patients at random divide into 2 group of, Chinese herbal medicine fine melt capsule treat group (32) And Rhubarb Zhe worm capsules contrast group (31). Medicine used 3 months behind, Observes two groups of's clinical curative effect. To symptom, Body enlists proceed record grade, And checkouts curative effect target:Liver function target (ALT, AST, GGT, ALP, ALB, A/G, TBil), Cholinesterase (CHE), prothrombin activity (PTA) (%), Blood serum liver fiber melt target (hyaluronic acid (HA), Laminin (LN), Procollagen Typeâ…¢(PC-â…¢), type IV collagen (â…£-C)), the marking of serum virus aetiology and abdomen colorful exceed check liver fiber melt blood current kinetics target (Portal vein trunk inside diameter (Dpv), Spleen vein inside diameter (Dsv), Portal vein average blood current speed (Vpv), Portal vein blood flow (Q), Spleen thickness (st)), Abdomen colorful exceed checks liver spleen supersonic change target grade. Meanwhile monitors blood routine, urine routine, feces routine, electrocardiogram as well as Kidney function. At last conduct statistical analysis to determine drug efficiency and safety.Results:Has treat for 3 months behind, Two groups of at synthesizes curative effect, Herbalist doctor symptom curative effect, Recovers liver function, Reduces liver fiber melt target, Improves image learn wait for chief target aspect average have clinical curative effect, But as fine melt capsule group curative effect is better, compared with Rhubarb Zhe worm capsules group have statistical difference (P<0.05).Conclusions:Fine melt capsule has effective treatment on early cirrhosis, and is able to converse liver fiber melt, Delay cirrhosis course. It is worth further study and clinical application.