Analysis Of Related Factors Of Excessive Daytime Sleepiness In Adult Males With Obsructive Sleep Apnea Hyponpea Yndrome

Objective: To analyze correlations between obstructive sleep apnea hypopnea syndrome (OSAHS) and excessive daytime sleepiness (EDS). investigated correlations between EDS and age, body mass index (BMI), apnea hypopnea index (AHI), apnea index (AI), lowest nocturnal oxygen saturation (minimum Sp0₂), mean nocturnal oxygen saturation (mean Sp0₂), the sleep time that oxygen saturation are less than 90 % accounting for the percentage of total sleep time (TS90), arounsals, non-rapid eye movement sleep 1 accounting for the ratio of total sleep time (S1%), non-rapid eye movement sleep 2 accounting for the ratio of total sleep time (S2%), non-rapid eye movement sleep 1+2 accounting for the ratio of total sleep time (S1+2%), non-rapid eye movement sleep 3+4 accounting for the ratio of total sleep time (S3+4%), rapid eye movement sleep time accounting for the ratio of total sleep time (REM%), sleep efficiency.Methods: Diagnosed as OSAHS by polysomnography, Epworth Sleepiness Scale questionnaire score filled and height, weight measured, then body mass index (BMI) calculated. Based on Epworth Sleepiness Scale score, 64 adult male patients with OSAHS were divided into non-sleepiness, mild, moderate, severe sleepiness group. According to the practice management guidelines for OSAHS in 2002,the nocturnal oxygen saturation and AHI can be divided into normal blood oxygen group, mild low blood oxygen group, moderate low blood oxygen group and severely low blood oxygen group; mild, moderate and severe AHI.Analyzing factors that affect the OSAHS patients'EDS.Results: In the OSAHS patients enrolled, mild and moderate sleepiness group accounted for a higher proportion. In four different levels of sleepiness in patients with OSAHS, AHI, AI and TS90 increased with aggravation of severity of sleepiness. AHI and TS90 of severe sleepiness group compared with that of non-sleepiness group, there was statistical significance(P<0.05), but that of mild and moderate sleepiness groups compared with non-sleepiness group, there was no statistical significance. AI of moderate and heavy sleepiness grouop compared with that of non-sleepiness group, there was statistical significance, but that of mild sleepiness group compared with non-sleepiness group, there was no statistical significance. Mean Sp0₂ of severe sleepiness group compared with the non-sleepiness group, there was significant difference(P<0.05), but that of mild and moderate sleepiness groups compared with non-sleepiness group, there was no statistical significance. S1+2% of severe sleepiness group compared with that of non- sleepiness group, there was statisticaly significant(t =- 2.402, P<0.05), but that of mild and moderate sleepiness groups compared with non-sleepiness group, there was no statistical significance. S3+4% and sleep efficiency of moderate and severe sleepiness group compared with that of non-sleepiness group respectively, there was statistical significance(P<0.05), but that of mild sleepiness group compared with non-sleepiness group, there was no statistical significance. With mean Sp0₂ decline ,the ESS score of different degree of mean Sp0₂ OSAHS patients increased. Moderate low blood oxygen group and severely low blood oxygen group compared with normal blood oxygen respectively, there was statistical significance(P<0.05);but that of different degree lowest blood oxygen saturation OSAHS groups of patients, there was no statistical significance.S1+2% of severe sleepiness group is high, sleep efficiency, S3+4% decreased with increasing sleepiness. There were positive correlations between ESS score and AHI, AI, HI, TS90. There were negative correlations between ESS score and mean Sp0₂, sleep efficiency. While confounding factors were ruled out, there were positive correlation between sleepiness and AHI, TS90, a negative correlation between sleepiness and sleep efficiency and no correlation between sleep and arousals.Conclusion: OSAHS patients'EDS is closely related with AHI, AI, noctural minimum Sp0₂, nocturnal Sp0₂, TS90, S1+2%, S3+4% and sleepiness efficiency. Factors above affects severity of OSAHS patients'EDS. The higher AHI is, the more severe hypoxemia will be, the longer duration will be, the greater proportion light sleep will account for, the smaller proportion deep sleep will account for, the poorer sleep efficiency will be, the more severe OSAHS patients'EDS will be.