A Comparison Research Of Laparoscopic Surgery For Early Diagnosis And Treatment Of Gastrointestinal Trauma Versus Open Surgery In Biochemistry And Immune System

ObjectiveTo establish a porcine model of intestinal firearm-trauma. To compare minimally invasive surgical approach with the traditional open surgical approach in the gastrointestinal trauma.MethodsTo establish experimental animal model of intestinal firearm-trauma. Design the fixed troca location and a reasonable abdominal exploration path of the minimally invasive approach.15 animals were randomly divided into the minimally invasive surgery group which contains 7 and open surgery group which contains 8. After surgeries, the two groups compared biochemical and immunological indicators to show the advantages and disadvantages between the two groups.ResultAll 15 animals were successfully survived 72 hours, with 13 animals had intestinal damage, accounting for 86.67% of the total number of animals; 5 cecal injury occurred, accounting for 33.33%; 4 sigmoid colon injury occurred, accounting for 26.67%; a bladder appears Injury, accounting for 6.67%. The amount of intra-abdominal hemorrhage is 5～250ml, an average of 70.7±21.5ml. No the liver, spleen, pancreas, kidney and other organ damage appear, no large blood vessel rupture. Weight, venous catheter time, anesthetic and surgical time was no significant difference, p> 0.05. Open group and the endoscopic group at each time point of white blood cells, red blood cells, total bilirubin, serum creatinine, serum potassium, serum sodium, glucocorticoids and C-reactive protein had no significant statistical difference (p> 0.05). White blood cells in experimental animals reach to the peak at 24 hours after operation, after 72 hours down to the preoperative level. White blood cells, red blood cells, total bilirubin, serum creatinine, serum potassium, serum sodium change before and after surgery was no significant difference, p> 0.05. Glucocorticoid and C-reactive protein significantly increased after operation, p<0.05, after 72 hours have not yet come down to normal.ConclusionThis study successfully creates the pig model of firearm injuries in the small intestine, which is stable and can be well-used to firearm injury of the small intestine. Solve the experimental animals perioperative safety, make the experimental animals tolerate surgeries more easy, convenient the salvage in operation, easy the draw blood post operation, to ensure the smooth progress of the experiment. For abdominal trauma, laparoscopic surgery does not cause more stress to the body, and good laparoscopic vision, rapid recovery, shorter treatment cycles, reduce postoperative complications and so that it can detect abdominal injury as a priority choice.