| Backgroundprimary bronchogenic carcinoma (Lung cancer) is one of the malignant tumor, seriously hazard to humans'health. Currently it is the cancer th at ranked the world's highest morbidity and mortality. investigation sta tistics showed by The World Health Organization (WHO), there are more t han 120 million new lung cancer patients worldwide each year, the number of people die of lung cancer is about 70 million. For modern medicine, W estern medicine therapy to lung cancer mainly are surgery, chemotherapy and radiotherapy. and intervention biological therapy, gene therapy, immu ne therapy, and so on. but its effect is not definite, yet has not bee n clinical widely generalized. Based on the limitations and effective ness of modern medicine treatment of lung cancer, to find effective tr eatment from traditional Chinese medicine, especially treatment for the 1 ocal symptom that aimed directly at the patients quality of life, and such treatment is a hot issue of oncotherapy.a large number of clinic al practice and experimental research indicating that traditional Chinese medicine has a certain effect of anti-tumor, and able to regulate bo dy immunity, reduce the clinical symptoms, can improve the patients quali ty of life of and prolong survival in patientsAsthma is one of the most common symptoms of lung cancer, asthma of lung cancer mostly accompany with symptoms as cough, bloody sputum, chest tightness, chest pain and so on, which seriously impact on patients quality of life. Clinical observation shows more than 70% of patients accompanied with asthma, it reduced patients'quality of life from the psychological, physical, spiritual and other aspects.whether asthma symptoms can get adequate treatment not directly related to the integral treatment of lung cancer, which is also one of most important reasons that confidence in. Therefore, the treatment to asthma can not be ignored during the treatment process of advanced lung cancer.Chuankezhi is two types of medicines in the nation, the main composition is a Yin Yang Huo and Ba Ji Tian, the Yin Yang Huo implies Yin Yang Huo many sugar, Yin Yang Huo Mao, Yin Yang Huo flavonoid etc. various valid compositions;Ba Ji Tian implies single sugar, many sugar, resin, vitamin C, have to amino acids, metals chemical element etc., Chuankezhi can the equipment has Wen Yang restore virility, even Chuankezhi to stop coughing of effect, start used for most clinical mainly is etc. which cures bronchus asthma and bronchitis disease, along with the recent years thorough research concerning that medicine, discover that that medicine has an usage convenience, poisonous the side effect be small, regulate human body immunity dint, the anti-lump is effective to wait a characteristics, at clinical up have vast usage foreground. The this topic dint diagram passes observation analysis to Chuankezhi acupuncture points to inject treatment kidney sun falsely type later period lung cancer asthma of clinical curative effect, provide new way of thinking for its clinical treatment.ObjectiveThrough clinical observation, objectivly evaluate the efficacy of C huankezhi Injection in the treatment of asthma accompanied with advanced lung cancer, to investigate the effective treatment for kidney yang d efficiency type of asthma of advanced lung cancer. and to provide basic medical foundation for Chuankezhi injection in the treatment of advance d lung cancer.Methodsapply The clinical research method, by means of single-blind prospec tive randomized controlled study, to establish the sample diagnostic cri teria, internalization criteria, exclusion criteria and the suspension of clinical trial standards. Observed 60 cases of hospitalized patients, wh ich were randomly assigned to treatment group of 30 patients, while 30 pa tients in the control group. in the control group:apply physiological saline with aminophylline injection. to inject Saline in the acupoi nt,which located on dual fei Shu and zusanli, per acupoint 2ml, one time every day. Aminophylline injection, in the way of intravenous infu sion, one time 0.25g diluted to 5% to 10% 250ml glucose injection, and s lowly drip. Treatment group:apply The Chuankezhi injection and aminophy lline injection, to inject Chuankezhi Injection in the acupoint, which 1 ocated on dual fei Shu and zusanli, per acupoint 2ml, one time every day. Aminophylline injection, in the way of intravenous infusion, one ti me 0.25g diluted to 5% to 10% 250ml glucose injection, and slowly drip. Recorded improve symptom and living quality of life rating scales before and after each course of treatment and analyze the data.Resultsthe effective power of The treatment group was 73.3%, and the control group was 40%,;to compare the efficiency of the two groups, by chi square test, P<0.05, the difference has statistical significance, indicating that in the treatment of asthma caused by lung cancer, the efficacy of the treatment group is better than the control group. In the comparison of the observed indicators, the treatment group before and after treatment and interblock after treatment, indicators such as coughing, wheezing, shortness of breath, weak waist, aversion to cold, apathetic were statistically significant by statistical analysis (P<0.05), but there is no improvement in sputum volume not only the treatment group but the control group, (P>0.05), indicating that in the treatment of asthma caused by lung cancer and kidney yang defficiency symptoms, the treatment group is superior to the control group, while in the improvement of sputum is not obvious. Treatment group and control group on quality of life, Karnofsky score and improvement in immune parameters, by t test, P were<0.05 and> 0.05, indicating that treatment can significantly improve the patients quality of life and immune function. To appear abrupt asthma of circumstance improvement, treatment set treatment in front and back cure an empress with two sets of set compare, through t examination, all have covariance to learn meaning. (P<0.05). Safety indicators, liver and kidney function were not different before and after treatment in both groups, but the impact on the blood, treatment group had higher white blood cell and red blood cells, by the statistical analysis, there were statistically significance (P<0.05) and the comparison between the two groups after treatment through statistical analysis, there are statistically significance (P<0.05), which shows from the other side, that treatment group can improve the immunity of patients, but also show that the in the treatment of asthma, the treatment group applied aminophylline and Chuankezhi injecta to inject to the acupuncture point has a good safety and reliability.ConelusionsChuankezhi injecta inject to the acupoint is an effective means of treatment to control kidney yang defficiency lung cancer asthma,based on Western medicine conventional therapy, plus the use of Chuankezhi injecta inject to the acupoint can significantly enhance the efficacy, improve patients'living quality of life, reduce patients'pain, and reduce toxicity in a certain degree. Therefore, the clinical treatment can be used as one of the means of asthma treatment of lung cancer. Chuankezhi injecta inject to the acupoint is simple, easy to operate, and secure, worthy of further promotion.
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