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Study On Labeled Technology And Quality Of Eucommiae Cortex

Posted on:2012-11-01Degree:MasterType:Thesis
Country:ChinaCandidate:Y QingFull Text:PDF
GTID:2154330335477464Subject:Pharmacognosy
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Eucommiae Cortex is the dried bark of the plant Eucommia ulmoides Oliv. of family Eucommiaceae. Perennial deciduous trees with a long history is China's cultivation unique medicinal plants.The drug is mainly produced in Sichuan, Shanxi, Hubei, Henan, Guizhou, Hunan and other areas.This research is part of the "11th five-year plan" national science and technology support programs - major initiative -- a "new project researching and developing TCM standard substance of technical platforms" issue "standard material calibration standard and stability technical specifications".According to the subject of relevant provisions, We research the characters,identify,Inspection, extract and the content determination on the samples which collected in 7 provinces in main plant area, such as sichuan, guizhou, hunan, hubei, gansu, shanxi, henan. Formulated the standard of calibration technology control medicinal materials of Eucommiae Cortex.Establishing standerd on characters,identify,Inspection, extract and the content determination inThe technical standard of calibration control medicinal materials of Eucommiae Cortex。Providing moisture not cross over 13.0% respectively; Total ash not cross over 10.0%; Extract should not be less than 11.0%;The amount of Pinoresinol Diglucoside should not be less than 0.10%; adding the acid not soluble ash should not cross over 6% and flavonoids content in should not be less than 0.7%; First established eucommia organic acid kind and lignanoids thin layer identification method.First established high performance liquid feature mapping in comparison with pinoresinol Diglucoside and Syringaresinol.This paper first adopted weighted pointrating method analysis effective constituent of 15 different origins eucommia (extract, Pinoresinol Diglucoside, flavone). First use icp-ms technology analysis trace selenium, heavy metals and harmful elements in 15 different origins eucommia. First by gas chromatography.the organic pesticide residues in eucommia ulmoides were studied. Combining effective composition and safety evaluation.Draw a conclusion that the Eucommiae Cortex which producted in Najiang,Bazhong,Sichuan province is the best medicine.This paper also compare research on eucommia and eucommla ulmoides effective components, safety, feature mapping. Results showed that eucommia and eucommla ulmoides effective component content and features mapping have obvious differences. Provide the basis for the rational use of Eucommiae.Based on the systematic study on eucommia ulmoides oliv produced different origins, established a perfect control medicinal materials calibration technical standard eucommia ulmoides.This standard should apply to proprietary Chinese medicine formula of eucommia ulmoides in medicinal preparation, can guarantee the appraisal of eucommia ulmoides clinical effect.At the same time, through the origin of eucommia ulmoides quality evaluation of study (effective ingredients and safety evaluation), for clinical rational selection and utilization of eucommia medicinal material provides actual basis.
Keywords/Search Tags:Eucommiae Cortex, Technical standard, High performance liquid feature mapping, Quality evaluation, Heavy metal and the harmful elements
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