Evaluation Of Left Ventricular Synchronicity And Function In Patients With Premature Ventricular Beat From Right Ventricular Outflow Tract By Omni-directional M-mode Echocardiography

Objective: To evaluate the left ventricular synchronicity and function in patients with premature ventricular beat(PVB) from right ventricular outflow tract (RVOT) with omni-directional M-mode echocardiography(OME).Methods: LV functions were analyzed with conventional echocardiography and LEJ-2 OME in 30 patients with PVB and in 30 normal subjects. Besides the routine parameters (LA,LV,IVS,EDV,EF,Sa,Vp,Ea,Ea/Aa, etc.), the time to peak myocardial systolic velocities (Ts) and the time to peak myocardial early-diastolic velocities(Td) were obtained from the velocity- time curves of 6 segments of the LV short axis view at the level of papillary muscles by OME,.the standard deviation of Ts,Td(Ts-6 -SD, Ts-6 -SD) were used as indicators of left ventricular dyssynchrony. The time to peak radial systolic strain (Trs) and peak radial early-diastolic strain (Trd) of LV in 6 segments were measured with two-dimensional strain and its standard deviation (Trs-6- SD), and (Trd-6- SD)were calculated. The relation between omni- directional M-mode echocardiography and speckle tracking imaging (STI) was analyzed.Reaults: 1.Compared with control group, there were no significant differences in the index of LA,LV,IVS,EDV,EF,Sa,Vp,Ea,Ea/Aa,Ts and Td (P>0.05), while Ts-6-SD and Td-6 -SD were significantly longer in PVB group in the normal sinus beat (P<0.05). 2.Compared with the normal sinus beat, LV,EDV,EF,Sa,Vp,Ea,Ea/Aa were significantly lower, while Ts,Td ,Ts-6-SD and Td-6 -SD were significantly longer in PVB (P<0.01).3. OME derived synchronization parameters correlated with STI derived synchronization parameters ( P<0.01 ), The assessment of left ventricular synchronicity base on OME is corresponding to STI (Kappa>0).Conclusions: The standard deviation the time to peak myocardial velocities can reflect the left ventricular synchronicity and function of the patients with PVB from RVOT.PVB from RVOT could significantly influence the left ventricular systolic and diastolic synchrony, omni-directional M-mode echocardiography is a new way to quantitatively assess the radial synchrony of the left ventricular.