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Clinical Features And Recent Prognosis Factores Analysis Of Peripartum Cardiomyopathy In 62 Cases

Posted on:2012-01-16Degree:MasterType:Thesis
Country:ChinaCandidate:L L HouFull Text:PDF
GTID:2154330335981181Subject:Internal Medicine
Abstract/Summary:
ObjectiveTo summarize the clinical manifestation and related exmination of peripartum cardiomyopathy in order to discover it,s clinical features and recent prognosis factores .Methods62 PPCM patients who were diagnosed as PPCM in The First Affiliated Hospital of An Hui Medical University from Jan 2001 to Jan 2011 were studied retrospectively. All of their clinical manifestations, EKG changes,chest X-ray,blood exmination UCG features,treatments and outcomes were analyzed.Results1. Formal material features: 35 older mothers (age≥30 years old) (56.5%), 40 rural patients (64.5%), 33 primiparas (53.2%), 59 only-child patients (95.2%), 37 caesarean patients (72.6%), 45 patients breaking after childbirth (72.6%), 23 with anemia (hemoglobin≤110g/L) (37.1%), 22 with infection (35.5%), 14 with hypertension (22.6%) in 62 patients.2. Clinical characteristics: All PPCM patients were presented with heart failure., Class III ( NYHA cardiac function classification ) for 32 cases(51.6%) and Class IV for 30 cases(48.4%). 43 patients were sent to hospital for the first time because of cardiac arrhythmia,chest distress,night paroxysmal dyspnea .3. Related examination outcomes: 40 patients, electrocardiogram (64.5%) present SVT and 60 patients, chest X-ray present cardiac enlargement.Out of 60 patients (96.8%) whose UCG present cardiacenlargement,21 patients, left atrium and left ventricle (39.9%) enlarge, 20 patients, left ventricle (32.3%) enlarge and 19 patients, whole hert (30.6%) enlarge.44 patients, UCG (71%) present systole activity inhabition.LVID mean is 57.06±5.82mm and LVEF mean is 45.13±6.1%. All PPCM patients were presented with heart failure: Class III ( NYHA cardiac function classification ) for 32 cases and Class IV for 30 cases. LVID of Class III is 5.55±0.59,LVID of Class IV is 5.87±0.53, P=0.027; LVEF of Class III is 0.47±0.06, LVEF of Class IV is 0.41±0.06,P=0.011. The difference between the two groups were significant. 4.Treatment of outcomes and prognosis :Through a series of treatment such as rest,oxygen uptaking,Increase myocardial contraction forces,diuresis,enlarging vascular infective,anti-freezing and so on,clinical symptoms of patients can be relieved or disappeaed. 14 cases were markedly,43 cases were effective and 5 cases were invalid. 18 patients examine UCG again before leaveing hospital, LVD:P=0.011,LVEF:P=0.000,the difference is significant. LVD and LVEF may the influencing factor of prognosis.Conclusions62 patients with peripartum cardiomyopathy in my hospital have no significant difference with International Epidemiology. 69.4% patients were sent to hospital for the first time because of acute left heart failure. 64.5% patients, electrocardiogram present SVT .96.8% patients have cardiacenlargement. Through timely diagnosis and treatment , most of these patients improved. LVD and LVEF may the recent influencing factor of prognosis.
Keywords/Search Tags:Peripartum Cardiomyopathy, Heart Failure, Prognosis
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