Systematic Review Of Unilateral Testicular Torsion Effects On Male Fertility

Objective: To evaluate the ability of testicular torsion effects on male fertility, for further clinical research and medical practice to provide references.Materials and Methods: In accordance with strict inclusion and exclusion criteria and pre-developed search strategy, the following databases of the Cochrane Upper Gastro-intestinal and Pancreatic Group specialised register, Cochrane Central Register of Controlled Trials, PubMed(1950~2011.2),MEDLINE(1950~2011.2),EMBASE(1980~2011.2), CNKI,CBM and VIP(1989~2011.2).Only RCT or CCT meet the entry criteria. Meta-analysis software was Stata11.0 provided by Cochrane collaboration net.Results: Eleven trial content 207 patients with unilateral testicular torsion meet the entry criteria. Meta analysis results showed that there was no statistic significance in the incidence of oligospermatism between the orchiectomy group and the orchiopexy group [OR = 1.365,95% CI (0.703,2.651) , P = 0.358,> 0.05]. But the effects on serum FSH levels between the two groups did have statistic significance [MD = 2.674,95% CI (1.736 ~ 3.612), P = 0.000, <0.005],the risk of the orchiectomy group is higher than that of the orchiopexy.Conclusion: The available evidence suggests that unilateral testicular torsion will to some extent damage male fertility, while the existing data still shows both the advantages and disadvantages of different surgical approaches, but does not advocate the relaxation of the orchiectomy indications. Further conclusions to be more the appearance of high quality clinical control study.