The Effects Of Serum Sodium Level Before The Endoscopic Variceal Ligation On Rehemorrhage And Survival In Patients With Liver Cirrhosis

Background and aims::Liver cirrhosis is the end-stage liver disease,and esophageal variceal hemorrhage is a serious complication of cirrhosis. With the technology of EVL developed,the mortality of esophageal variceal hemorrhage has controlled,but some patients still has a poor prognosis. It was reported that MELD and MESO had a correlation with the prognosis,In this study ,we will analyze the effects of serum sodium level before the endoscopic variceal ligation(EVL) on the upper gastrointestinal rehemorrhage and survival after the EVL in the patients with liver cirrhosisMethods:The serum sodium concentrations of 218 patients before their EVL operations was classified into three groups(≥135mmol/L,125-135mmol/Land≤125mmol/L),and MELD scores were calculated among 218 patients before their EVL operations. After the EVL these patients were followed-up ,and the survival and probability of rehemorrhage were analyzed.Results: In the 218 patients, the mean survival of the serum sodium concentration (≥135mmol/L) was 69.11months,the mean survival of the serum sodium concentration (125 -135mmol/L) was 63.33 months,and the mean survival of the serum sodium concentration(≤125mmol/L) was only 47.42 months. With the serum sodium level decreasing,the incidence of rehemorrhage increased during 6 years after the first EVL. In the three groups of MELD scores(≤7,7-9,≥9), the mean of survival were 70.36, 69.86, 48.79 months respectively.Combining with the serum sodium level, MELD scores(>9)could assess the cause of death more precisely.Conclusions : Both the serum sodium level and MELD scores could predict the rehemorrhage and survival,but the serum sodium level was better than MELD scores in shorter periods.