Study Of Ultrasonic Elastography Applied In Differential Diagnosis Of Benign And Malignant Of Solid Breast Lesions

ObjectiveTo investigate the value of ultrasonic elastography(UE) in the qualitative diagnosis of breast lesions, provide more information and for the therapy and diagnosis of the breast cancer.MethodsCUS and UE was used to examine a total of 139 patients with 162 breast lesions. Using surgical pathology as the golden standard, while the number of benign lesions is 104, the number of malignant lesions is 58. To compare the sensitivity, specificity, Observing morphology, echo, boundary, capsule, blood flow grading, Ri, the area ratio of lesions in CUS and UE(area ratio), and comparing the sentivity(Sen), specificity(Spe), crude accuracy(CA), positive predicitive value (PV+) and negetive (PV-) of UE and CUS , CUS itself and diagnosing breast lesions by UE score and area ratio after they were found by Two-dimensional Ultrasound(2D-US).Results1,Morphology, boundary, capsule, microcalciffcation, high-level echo layer, blood flow grading, RI, UE score and area ratio of benign and malignant breast lesions are significant difference statistically (P<0.01); the internal echo of breast benign and malignant lesions were different statistically (P<0.05).2,After breast lesions were found by T2D-US, diagnosing them by UE score and area ratio higher statistically than by area ratio(1.5) in Sen(P<0.05). Diagnosing them by UE score(grade 3) was much higher statistically than by area ratio(1.5) in Sen(P<0.01);Diagnosing them by UE score and area ratio, by UE score(grade 4), by UE score(grade 3) weren't different statistically in Sen (P>0.05).3,After breast lesions were found by 2D-US, diagnosing them by UE score and area ratio, by UE score (grade3), UE score (grade4) were higher statistically than by area ratio(1.5) in Spe (P<0.05); diagnosing them by the fomoral three methods aren't different statistically in Spe(P < 0.05). Four methods weren't different statistically in CA (P>0.05)4,Diagnosing breast lesions by UE and CUS was higer statistically than CUS itself in Spe (P<0.05). After breast lesions were found by 2D-US, diagnosing them by UE score and area ratio was much higer statistically than CUS itself in Spe(P<0.05). UE and CUS, diagnosing them by UE score and area ratio after breast lesions were found by 2D-US, CUS itself aren't different statistically in Spe(P>0.05).5,Diagnosing breast lesions by UE and CUS was higer statistically than CUS itself in Spe and CA(P<0.05).UE and CUS Diagnosing breast lesions by UE and CUS was higer statistically than CUS itself in Spe and CA(P<0.05). After breast lesions were found by 2D-US, diagnosing them by UE score and area ratio was much higer statistically than CUS itself in CA(P<0.05). UE and CUS, diagnosing them by UE score and area ratio after breast lesions were found by 2D-US, CUS itself aren't different statistically in Sen(P>0.05).Conclusions1,UE score, area ratio is important clinical value in the different quality diagnosis of breast lesions.2,The size of breast, growing-time, liquefaction, calcification and fiberiz- ation of lesions are influent to UE score.3,After breast lesions were found by 2D-US, diagnosing them by UE score and area ratio was higer in Spe, but it wasn't higer than CUS itself in Sen and CA. UE and CUS message is helpful to diagnosing in the different quality diagnosis of breast lesions and diagnosing in accuracy.