Optimization Of Technical Parameters Of Susceptibility Weighted Imaging In The Liver And The Clinic Application In Discovery And Diagnosis Of Focal Liver Lesions

Objective To evaluate parameters of susceptibility weighted imaging in the liver.Methods SWI of the liver was performed in 20 healthy adult volunteers. Different parameters include SENSE factor and number of excitation. SWI in liver was performed with different factor of SENSE including 1,1.5,2.5 and 3.5; and different number of excitation including 1,2,3.Results SWI with SENSE of 1.5 was better than that with 1,2.5 and 3.5. SWI with 1 excitation showed higher quality than that with 2 and 3.Conclusion SWI with SENSE factor 1.5 and 1 excitation was the better in SWI of the liver. Objective To investigate the value of susceptibility weighted imaging in discovery and diagnosis of focal liver lesions.Methods Eighteen patients with 25 focal liver lesions were collected,all of them were proved by diagnosis of clinic and imaging. It included liver vascular malformation (n=1),hepatocellular carcinoma (n =4), cholangiocellular carcinoma(n=3), metastatic tumor in liver(n=2), liver haemangioma (n=5), and liver cyst (n=3). MR imaging were performed with conventional T1WI, T2WI, SWI and dynamic Gd-DTPA contrast enhanced MRI.liver vascular malformation(n=1) performed 3DMRA and post-gadolinium enhanced SWI in one liver haemangioma was also obtained.Results:In liver Vascular malformation(n=1), SWI is better than conventional MRI and 3D-MRA in discovering anormally vein form. SWI could discover tumor vascular structure and degradation products of blood in hepatocellular carcinoma (n=4), cholangiocellular carcinoma (n=3) and metastatic tumor in liver(n=2). SWI showed uniformity slightly hypso-signal in liver haemangioma (n=5) and liver cyst (n=3), and in comparatively large lesion of which the neighbourhood vein was compressed. Conclusion:SWI was surpassed than conventional MRI sequences in discover liver venous Vascular malformation and vascular structure correlated in tumor. SWI is very helpful in differential diagnosis of focal liver lesions, It was a new approach to investigate the internal structures of focal liver lesions.