The Analysis Of Relative Factors Of Residual Lesion In Cervix After Loop Electrosurgical Excision Procedures In Patients With Cervical Intraepithelial Neoplasia

To determine the elinicopathological factors connectting to residual lesions after loop electrosurgical excision procedures (LEEP) in patients with cervical intraepithelial neoplasia(CIN)and microinvasive carcinoma of cervix(MIC) for guiding the follow-up and the treatment of those patients,1.collect the clinical data of 37 patients with CINⅢ,2 patients with stageⅠa1 orⅠa2 cervical cancer, totally 75 patients, who received further surgery or other treatment within 3 months after conization were evaluated.The follow treatments are colposcope and pathological examination under colposcope.2.The demographic features,clinical and pathological parametersand,and the correlation thereof with the post-conization residual lesions were analyzed retrospectively.1.In 75 patients,the age rage is (45±6),and 37 patients with CINⅢ, 2 patients with stageⅠa1 orⅠa2 cervical cancer is included.Residual lesions were found in the specimens obtained from hysterectomy or repeated eonization of 38 of the 75 patients(50.7%), among which 35 were CINⅡor less severe lesions.2.Univariate analysis showed that menopausal status,procreation status,cervical cytology and range of reflection were not correlated with the presence of post-conization residual lesion,While the age≤40, high-risk HPV infection and positive resection margin(P<0.05) was the risk factors of residual lesion. There were no differences in the proportion of post-conization residual lesion among the patients with MIC, CINⅡ, CINⅢor less severe lesions.3.Multivariate logistic analysis showed that the high-risk HPV infection and the positive resection margin were independent risk factors of residual lesion after conization.[P<0.05].The HRHPV infection and the positive resection margin were independent risk factors of residual lesion after LEEP.