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Analysis Of The Related Factors Of Survival And Life Quality Of Postoperation Esophageal Cancer

Posted on:2011-06-18Degree:MasterType:Thesis
Country:ChinaCandidate:Y C LiFull Text:PDF
GTID:2154360308485068Subject:Department of Cardiothoracic Surgery
Abstract/Summary:PDF Full Text Request
Objective: The survival rate and quality of life after Esophageal Cancer operation affected by various factors, such as age, preoperative cardiopulmonary function, surgical incision, digestive tract reconstruction, clinical stage, postoperative complications, postoperative chemotherapy, nutrition, mental factors and so on. This paper discusses the clinical stage, lymph node metastases and postoperative chemotherapy on Survival rate and postoperative quality of life after esophageal cancer operation.Methods: A total of 227 cases with esophageal carcinoma underwent radical esophagectomy with complete data who were admitted to 1st Affiliated Hospital of Shantou University Medical College between 2003 and 2010 were selected in this study.Followed up these 227 cases by telephone connection or home visit, analyze the related factors for survival rates and quality of life after esophageal cancer operation. Analyzed the survival rates by Kaplan - Meier method; Analyzed the survival differences by Log - Rank test comparison; Analyzed the the quality of life score by T test.Results: The affect of Different clinical stages on the survival rate is statistical significance, P <0.01.In this group, of Stageâ… &â…¡a,â…¡b,â…¢andâ…£is 91.7%, 86.8%, 65.4% and 40% , 3 year survival rate is 71.3%, 50.2%, 38.1 and 40%;5 year survival rate 63.3%, 40.2%, 38.1% and 20%. P < 0.01, it is significant. Lymph node metastasis on the survival rate, P < 0.01, it is significant.Postoperative chemotherapy on the survival rate, P > 0.05, the difference was not statistically significant. The affect of Different clinical stages on quality of life is statistical significance, P < 0.01 and it is significant differences (comparison between stageâ… +â…¡a andâ…¢) . Compared the life quality of Patients with positive lymph node metastasis and patients with negative lymph node metastasis, P < 0.05, both groups was statistically significant. Postoperative chemotherapy on the quality of life had no significant impact, P > 0.05.Conclusions: In this study population, clinical stage on survival rates and quality of life had significant correlation. Lymph node metastasis on survival rates and quality of life had significant correlation.Postoperative chemotherapy on survival rates and quality of life had no significant correlation.
Keywords/Search Tags:Esophageal cancer, surgical treatment, survival rates, quality of life (QOL), Clinical stage, Lymph node metastasis, postoperative chemotherapy
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