Tangzhiping Particles On Impaired Glucose Tolerance (IGT) Phlegm And Blood Stasis Clinical

Objective:1.The discussion Tangzhiping particles to delays the IGT transformation is 2 diabetes' clinical curative effect observations 2.Discussion Tangzhiping particles to IGT patient waist, body weight index, blood pressure, sugar fat metabolism target, HbAlc influence.3. Analysis insulin sensitive index and IGT patient various metabolism target relevance.Methods:A randomized, controlled prospective study,30 cases were phlegm and blood stasis dialectical card IGT were randomly divided into control group and the Chinese intervention group. Data of sex, age, duration and other clinical characteristics, the control group only received routine lifestyle intervention; Chinese intervention in the lifestyle intervention group, while glucose and lipid levels for particles. Baseline testing and observation in December when the lipid metabolism, blood pressure, waist circumference, body mass index, every March retest 2h fasting and postprandial glucose, a standard OGTT test assessing whether the IGT patients into DM. Were compared before and after treatment (baseline and 12 months) by the IGT into differences in risk of diabetes and related metabolic changes in different indicators.Results:(1)Chinese intervention and control groups the conversion of IGT to DM were 10% and 30%, but the difference was not statistically significant (n=20, P> 0.05). (2) Chinese intervention and control groups before and after treatment Wc, BMI, systolic blood pressure, glucose and lipid metabolism, HbAlc change was no significant difference (P> 0.05). Chinese intervention group DBP after treatment than before treatment were significantly lower (77.00±5.16 vs 83.700±57.76,P<0.05).Conclusions:(1) Chinese Tangzhiping particles in the slow conversion rate of IGT to DM might have some positive effects. (2) Chinese Tangzhiping particles may have reduced the role of diastolic blood pressure in the lower AST and ALT may have a role. (3)further evidence of obesity, especially abdominal obesity is an important factor causing insulin resistance.