Study On Tranditional Chinese Medicine Regulation Of Symdrome-Treatment Of Sjogren Syndrome

[Objective]On the basis of collecting and analyzing the materials concerning the treatment of Sjogren syndrome with Chinese medicinal in recent 15 years in China; and to explore the distribute regulation of SS by investigation of clinical patients. Then apply reference could be provided for clinical medication and basal research by discuSSing the syndrome differentiation and treatment of SS.[Methods]Through looking up and arranging literatures about SS in recent years; Retrospective investigation and analysis were carried out in 110 cases of SS, Syndromes of the collected clinical data inducted to SPSS13.0 were claSSified, and the relationship of all syndromes with attacking principle of treatment were analyzed respectively. Syndrome of traditional Chinese medicine (TCM) and the rule of determination of treatment.[Results]First:literature researchFor SS, Liver and kidney yin deficiency or lung and stomach yin deficiency is the main, with qi deficiency, intermingled with dryneSS, toxico, heat, blood stasis, dampneSS, Syndrome of intermingled deficiency with exceSS is the characteristic of SS syndrome subject. The top three syndromes are pattern of deficiency of both qi and yin and accompanying symptoms of dryneSS toxin and deficiency syndrome of both liver and kidney yin, deficiency of qi and yin; The kidney, liver, and lung are the top three locations of syndromes elements; And yin asthenia, dryneSS and toxico are the top three pathogenesis types of syndromes elements. Nourishing yin drug, clearing heat drug, qi supplementing drug and blood activation drug are commonly used Chinese medicine. Method of nourishing yin and moistering arid is the principle of treatment in treating SS, nourishing spleen and enriching qi herbs, clearing heat and activating blood circulation act as main treatment means. The onset of SS has been found to be related to yin asthenia and saliva deficient, stagnation of vital energy and blood stasis, toxico and dryneSS; It's expounds the theoretical and clinical application, and nourishing yin, invigorating qi, clearing heat and Activating blood are used on treatment of SS.Second:clinical case researchThe thesis summarized the diagnosis and treatment of SS, by collecting 110 cases of SS and imputing them into databases. The result showed that the top three symptoms are dry mouth, dry eye or Paraesthesia eye, the four limbs feel weak. SS were divided into 6 syndrome types, Qi and yin deficiency is the majority type, approximately composes 31.82%, the main card sees the dry mouth, dry eye or Paraesthesia eye, dry cough, the four limbs feel weak, dizzineSS, short breath, night sweat, pale tongue or red tongue, thinneSS coating or exfoliation coating, dryneSS coating,, thready pulse or weak; Treatment method is nourishing yin to moisten dryneSS and invigorating qi. Liver and kidney yin deficiency is next best, approximately composes 30.00%; the main card sees the dry mouth, dry eye or Paraesthesia eye, dry skin, dry nasal cavity, feverish sensation of five centers, dry vagina, red tongue, exfoliation coating, dryneSS coating, thready pulse; Treatment method is nourishing yin to moisten dryneSS, reinforcing liver and kidney and enriching and promoting blood flow.Spleen Yin deficiency, approximately composes 14.55%; the main card sees the dry mouth, dry eye or Paraesthesia eye, dry excrement, dry skin, gastric absceSS and plenitude, poor appetite, red tongue, exfoliation coating, thready pulse; Treatment method is nourishing yin to moisten dryneSS, invigorating spleen and replenishing qi and activating blood and removing stasis. Deficiency of Yin with damp-heat, approximately composes 10.91%; the main card sees the dry mouth, dry eye or Paraesthesia eye, bitter taste of mouth, painful swelling of joint, poor appetite red tongue, yellowish and greasy coating, thready pulse or taut or slippery; Treatment method is invigorating spleen and replenishing qi, clear away damp elimination, removing dampneSS and activate qi. Deficiency of Qi, approximately composes 6.34%; the main card sees the dry mouth, not dry eye, the four limbs feel weak, red tongue, thinneSS coating, dryneSS coating, thready pulse; Treatment method is nourishing yin to moisten dryneSS, fortify the spleen and supplement qi and activating blood and removing stasis. Yin deficiency and blood tasis, approximately composes 6.34%; the main card sees the dry mouth, dry eye, dark complexion, Raynaud's phenomenon, painful swelling of joint, dark tongue, exfoliation coating, thready pulse or running or taut; Treatment method is nourishing yin to moisten dryneSS, activating blood and removing stasis and enriching and promoting blood flow.Method of nourishing yin and moistering arid is the principle of treatment in treating SS, invigorating spleen and replenishing qi and enriching and promoting blood flow act as main treatment means. In clinical treatment, treatment based on syndrome differentiation in TCM is more efficacious to certain extent.