Investigation And Study On Physical Type Of Traditional Chinese Medicine And Syndrome Differentiation Of Traditional Chinese Medicine With Regard To Non-small-cell Lung Cancer Patients

Objective:1) To clear the distribution of TCM constitution type and TCM syndrome differentiation of local area NSCLC patients with different stages.2) To figure out the correlation between TCM constitution type and TCM syndrome differentiation of local area NSCLC patients.Methods:This study draw on a prospective clinical research methods.170 cases of NSCLC patients which meet the income standard set were screened. Using the pre-designed objective, quantitative questionnaire, there TCM or Western medicine combined with professional post-graduate conducted a questionnaire survey of selected patients. After that an attending physician and a physician which are Specialized in TCM profession were responsible for determining and auditing of the TCM constitution type and TCM syndrome differentiation. Finally, according to the relevant criteria to determine the TCM constitution type and TCM syndrome differentiation of each NSCLC cases.Results:1) In terms of TCM constitution, among 170 cases, the main types are Qi Deficiency constitution(25.88%) and Phlegm-dampness constitution(18.82%), followed by Yang Deficiency constitution(14.12%), Dampness-heat constitution(12.94%),.TCM constitution have no association with age(P>0.05).2) About TCM syndrome differentiation, among 170 cases, the order listed by frequency are as follows:Qi Deficiency(22.94%), Blood stasis(17.06%), Phlegm-dampness syndrome(15.29%), Phlegm-heat syndrome(11.18%), Yin Deficiency(11.18%), Yang Deficiency(10.59%), Qi Stagnation(6.47%), No syndrome(3.53%), Blood Deficiency(1.76%). TCM syndrome differentiation have evident relation with Clinical-stage(P=0.043), but they have no association with Patho-category(P=0.142).3) The relationship between TCM constitution and TCM syndrome differentiation:the Qi Deficiency constitution mostly relates to Yang Deficiency syndrome, Blood stasis syndrome and Phlegm-heat syndrome(P<0.05). The Yin Deficiency constitution mostly relates to Yin Deficiency syndrome(P<0.05). The Phlegm-dampness constitution mostly relates to Phlegm-heat syndrome(P<0.05).Conclusions:1) The main constitution type of NSCLC patients are Qi Deficiency constitution and Phlegm-dampness constitution.2) In the TCM syndrome differentiation, Qi deficiency is mainly to Asthenia syndromes, Phlegm and Blood-stasis is mainly to Sthenia syndromes. So Qi deficiency, Phlegm-dampness and Blood-stasis are the most common TCM syndromes and the core of Pathogenesis in NSCLC, providing the theory evidence for it.3) The NSCLC patients of I, II are predominant in Sthenia syndrome, but with the progression of pathogenetic condition from morning to advanced stage,the syndromes would evolve from Sthenia syndrome to Asthenia and Sthenia syndrome, and vary into Asthenia syndrome at last, so the patients of III, IV are predominant in Asthenia and Sthenia syndrome, Asthenia syndrome.4) The TCM constitution type has a certain intrinsic correlation with the TCM syndrome differentiation. Therefore, in the process of Chinese medicine treatment of NSCLC, we should pay attention to the overall concept of TCM, not only to " distinguish syndrome for treatment" as well as attention to " distinguish constitution for treatment", to correct physical constitution, in order to achieve better efficacy.