The Correlation Of The Acupuncture's Clinical Effect With The Changes Of Medical Imaging And EEG Performance Reflect In The Movement Disordered Patients Caused By Brain Injury

Objective:Using prospective and retrospective methods to observe the clinical efficacy of acupuncture therapy in improving the motor function of patients with cerebral injury induced motor dysfunction. An attempt will be made to correlate the clinical efficacy of acupuncture therapy to clinical imaging and Encephalogram (EEG). The study will also objectively assess the efficacy of acupuncture therapy in treating motor dysfunction, and discuss the potential of using imaging and EEG as tools for evaluating disease prognosis.Method:Twenty-nine in-or outpatients with cerebral injury related motor dysfunction were selected from the department of Neurosurgery and Acupuncture Rehabilitation of the Fujian Second People's Hospital between November 2007 to February 2010. The inclusion criteria required that the patients had ongoing treatment for their primary diseases and were proactively controlling their blood pressures. Subjects received acupuncture that specifically aimed to improve circulation of the meridians and balance the flow of qi and blood. The treatment continued for 20 days. Subjects motor function performance before and after treatment were evaluated using Fugl-Meyer Assessment (FMA). Imaging examinations showing changes in sizes of intracranial lesions (hematoma, Low-density lesion) were correlated with subject's FMA scores. Six subjects underwent EEG examination and the results were correlated with FMA scores before and after treatment.Result:Significant differences (P<0.05) were found in FMA scores (Including muscle synergy of upper and lower extremities, whole body movement, stability of joint muscles, coordination and speed) before and after treatment, intracranial lesion sizes, as well as EEG activity in corresponding lesion areas. Improvements in motor functions showed linear correlation with EEG activity changes in corresponding lesion areas, but not with changes in size of intracranial lesions (P<0.05).Conclusion:Acupuncture therapy showed significant efficacy in improving dyskinesia, reducing intracranial lesion sizes, as well as in EEG.The EEG showed that the dysfunction-patients with cerebral injury were found brain wave lower in C3/C4 area, but not in other EEG leads. However the change of brain waves in C3/C4 area are related to the degree of the improving in motor functions.And while the improving in motor functions,the EEG may find significant change of brain waves in C3/C4 area but other leads. The motor function performances of patients with cerebral injury does not relate entirely to the intracranial lesion sizes,however it has in connection with the location of the lesion. EEG examination is a sensitive indicator that reflects the extent of brain tissue injury, and the effectiveness of clinical treatments. It could be used to determine the efficacy of rehabilitation treatments such as acupuncture.