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The Historical Cohort Studies Of Chinese Medicine Syndrome Type Distribution And Evolving Laws Around Gastric Cancer Operation

Posted on:2011-12-04Degree:MasterType:Thesis
Country:ChinaCandidate:Y J ZhanFull Text:PDF
GTID:2154360308981513Subject:Diagnostics of Chinese Medicine
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Objective of research:To explore and discuss the distribution of TCM syndromes and their evolutionanry rules before and after the gastric cancer Operation. Thus, supply a theoretical foundation for TCM in complementarily curing gastric cancer before and after gastric cancer OperationMethod of Reserch:Apply retrospective research mothed plus medical cases'collection techniques. Collecting patients'syndrome imformation pre and post operation, establishing the imformation platform for TCM syndrome in Carcinoma therapy. Input data obtained from clinic into computer and establish information database, then compute fluency and proportion to summarise commonly-seen syndromes before and after gastric cancer operation. Apply paired Chi-square test to make constrast among syndromes pre and post the surgery.Then sift those that potienally have clnical importance and statistical importance syndromes-changing. Finally deduce the evolution rule before and after the operations.Result:Make statistical analysis to the 105 patients pre and after Stomach Carcinoma Operation.Major symptoms are as follows:Pre:Discomfort at Stomach area, Stomachache(including dull pain, twinge, burning pain, and distending pain.), flatulence, inappetence, dysphagia, eructation, acid regurgitation, nausea, vomit, asthenia, sallow complexion, pallor complexion, autophagia, melena and ect.Postoperation period, except for the severity of asthenia, autophagia, sallow complexion and pallor complexion, other syptoms are all obviously relieved or disappeared.The result above indicates that patients of Stomach Carcinoma are commonly classfiled by Qi-defficiency Syndrome (manifested by asthenia ect.), Blood-deff iciency Syndrome (manifested by sallow complexion and pale ect.), Qi-stagnation Syndrome(flatulence ect.), Blood-stagnation (twinge and durative pain and melena). In postoperation period, the manifestations of Qi and Blood-Defficiency have become more severe while Qi-stagnation and Blood-stagnation syndrome have been relieved.The symptoms distribution of gastric cancer can be ranked as follows according to their percentage frequency (rate) from high to low:the disharmony of liver and stomach 28 (26.7%), qi stagnation 25(23.8%), spleen and stomach qi deficiency 19 (18.1%), blood deficiency 12 (11.4%), phlegm and stasis interwining together 9 (8.6%), spleen Deficiency 6 (5.7%) etc. Postoperation:spleen and stomach qi Defficiency 26(24.8%), Qi and Blood Deficiency 24(22.9%), Qi and Blood stagnation 19(18.1%), phlegm and stasis interwining together 14(13.3%), stomach and spleen Deficient Cold 9(8.6%), disharmony between liver and stomach 9(8.6%) etc.Conclusion of the study:The major syndromes in gastric cancer before and after the operation are of the same type, but their frequency in the team are very different. During preoperative period, the major syndromes are as follows:disharmony of liver and stomach, qi and blood stagnation, spleen qi deficiency syndrome while during postoperative period the major syndromes are spleen qi deficiency, qi and blood deficiency, phlegm and stasis interwining together syndromes. There is a significant proportion of their differences. Contrasting gastric surgery syndromes before and after surgery, we see its evolution are as follows:Qi stagnation syndrome declined, blood stasis reduced, Qi deficiency increased, blood deficiency increased. After statistical analysis, chi-square test P value<0.05, which means it is statistically significant.
Keywords/Search Tags:gastric cancer, Preoperation and postoperation, TCM Syndrome, evolutionary rule
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