Professor Yang Daowen 's Experience In Treating Pulmonary Fibrosis

Pulmonary Interstitial Fibrosis (PF) is the common ending of a range of Diffuse Interstitial Lung Disease (DILD). Most of the patients with PF were occult onset, their main clinical symptoms were cough, expectoration, chest tightness and shortness of breath. And with the development of the disease, progressive dyspnea may occur, eventually it will lead to respiratory failure. In recent years, we can see that the incidence of PF is increasing year by year, and the mortality is high, the prognosis is generally poor, which become one of clinical difficult disease. For the moment, the pathogeny of PF is not explicit, there are two main types of pulmonary fibrosis in clinic:Idiopathic Pulmonary Fibrosis (IPF) and Secondary Pulmonary Fibrosis (SPF).Now we diagnose this disease by clinical history, clinical symptoms, physical examination, laboratory examination, HRCT, examination, pulmonary function test, bronchoscopy, surgical lung biopsy and other tests. In the treatment, western medicine mainly treat PF by glucocorticoid, cytotoxic agents, anti fibrosis drugs and lung transplantation. But most of patients’ therapeutic effect is not ideal, and it may show more serious toxic side effects. So it got a big attention that we treat PF by our traditional Chinese medicine. Pulmonary fibrosis is the name of modern medical disease, and there is no record about the name of the disease in Chinese classical literature. According to the clinical symptoms, the clinical course of the disease, most doctors think PF will be classified as "Feiwei" category.The first part of this thesis is the collection of literature, which Focus on the summary of the ancient physicians for the comprehension of atrophic lung disease, contemporary physicians’ comprehension about the etiology, pathogenesis of pulmonary fibrosis, treatment experience and clinical curative effect observation. We can find that the traditional Chinese medicine for the disease awareness, treatment and research are becoming more mature, we also achieved good curative effect and opened up a new way to treat this disease.In the second part, I summarizes professor Yang Daowen’s experience about the treatment of pulmonary fibrosis patients, which based on the classic, the years of clinical practice and accumulation. It include the understanding on the etiology and mechanism of pulmonary fibrosis from Doctor Yang, herbal prescription, daily nursing, drug curative effect observation and clinical typical cases. He believes that block the progress of the disease, prolong the survival period, the prevention of acute attack and relieve symptoms are ultimate therapeutic targets。 At the same time, Yang think the day-to-day nursing also be important, including to get rid of the bad habits, adhere to long-term oxygen therapy and the necessary functional exercise etc.This part focuses on his characteristics of Chinese medicine for lung fibrosis. Yang believes that the main pathogenesis of atrophic lung disease is Lung-Kidney Deficiency, Phlegm-Dampness, Blood Stasis Syndrome. This disease belongs to asthenia and sthenia, deficiency of lung-kidney is asthenia, phlegm, blood stasis, external pathogens is sthenia. He thought FeiWei mainly occured in the lung, but it is related to the spleen and kidney. He often adopted Supplementing Qi and Activating Blood Circulation, Replenishing Qi of Lung and Kidney, and he liked to Heavy Raw Radix Astragali, emphasized functional activity of Qi and Blood.