Study On Distribution Regularity Of TCM Syndromes Of Nonvalvular Atrial Fibrillation

ObjectiveTo research the distributing disciplinarian of the traditional Chinese Medicine(TCM) syndrome patterns in non-valvular atrial fibrillation(NVAF) and then probe theoretical foundation for the treatment.MethodsFirstly,111 non-valvular atrial fibrillation patients,selected from the Orient hospital affiliated to BeiJing University of Chinese Medicine,during January 1,2012 to December 31,2015,were enrolled in our study with the clinical epidemiological study method.Then we used the clinical epidemic questionnaires of case for the non-valvular atrial fibrillation to collect the information of these qualified patients,including the general information,the information of TCM four diagnostic and the information of assistant examination.we collected the correction information of four diagnostic method And two vice director cardiologists who engaged in clinical work for a long time,were participating in our study and they made the new dialectics though the dialectics and the clinical symptom and signs at that time.Finally,the information of these qualified questionnaires were entering in the excel to establish the database.When the database was established,we managed and disposed the data with the SPSS17.0,and then analysis the TCM syndrome in the questionnaires,descriptive statistical analysis was widely used in our study. Results1.The traditional Chinese medicine syndrome of non-valvular atrial fibrillationdistributed as follow:Qi deficiency syndrome (89.2%)> Blood stasis syndrome (62.2%)>Phlegm turbidity syndrome (32.4%)>Yin deficiency syndrome (23.4%)>Blood deficiency syndrome (21.6%)>Yang deficiency syndrome (1.8%)=fluid retention syndrome (1.8%)>Qi stasis syndrome (0.9%). 2.The combination of the deficiency-syndrome of non-valvular atrial fibrillationdistributed as follow:the signal-syndrome (47 cases,42.3%)>the combination of two-syndromes (36 cases,32.4%)>the combination Of three-syndromes (22 cases,19.8%)>the combination Of four-syndromes (6 cases,5.4%).The traditional Chinese medicine syndrome distributed in the signal-syndrome as follow:Blood deficiency syndrome (24 cases,51.1%)>Blood stasis syndrome (11 cases,23.4%)>Yin deficiency syndrome (5 cases,10.6%)>fluid retention syndrome (2 cases,4.3%)>Yang deficiency syndrome (1 case,2.1%)>Qi deficiency syndrome (0 case,0%)=Qi stasis syndrome (0 case,0%).The traditional Chinese medicine syndrome distributed in the combination Of two-syndromes as follow:the combination of syndromes of the Qi deficiency syndrome and blood stasis (29 cases,80.6%)>the combination of syndromes of the Qi and yin deficiency syndrome (6 cases,16.7%)>the combination of syndromes of the Phlegm turbidity syndrome and Blood stasis syndrome (1 case,2.7%).The traditional Chinese medicine syndrome distributed in the combination Of three-syndromes as follow:the combination of syndromes of the Qi deficiency syndrome,blood stasis and Phlegm turbidity syndrome (14 cases,63.6%)>the combination of syndromes of the Qi deficiency syndrome,yin deficiency syndrome and blood stasis (7 cases,31.8%)>the combination of syndromes of the Qi deficiency syndrome,yin deficiency syndrome and blood stasis and Phlegm turbidity syndrome (1 case,4.5%).The traditional Chinese medicine syndrome distributed in the combination Of four-syndromes were the combination of syndromes of the Qi deficiency syndrome,yin deficiency syndrome,blood stasis and Phlegm turbidity syndrome (6 cases).Above of all,the combination of syndromes of the Qi deficiency syndrome and blood stasis (49 cases,44.1%)>the combination of syndromes of the blood stasis and Phlegm turbidity syndrome (21 cases,18.9%)>the combination of syndromes of the Qi deficiency syndrome and yin deficiency syndrome (20 cases,18.0%).3.The pathological viscera of non-valvular atrial fibrillation:the pathological viscera of non-valvular atrial fibrillation was mainly the heart and closely related to the spleen and the kidney.The distribution of the pathological viscera was as follow:spleen (49 cases,44.1%)>kidney (26 cases,23.4%)>lung (5 cases,4.5%)>liver (1 case,0.9%).4.The traditional Chinese medicine Syndrome regression analysis:Seeing non-valvular atrial fibrillation with Coronary heart disease(CHD) and without Coronary heart disease group as the dependent variable. And seeing Qi deficiency syndrome,Blood deficiency syndrome, Yin deficiency syndrome, Yang deficiency syndrome,Cold phlegm syndrome,Phlegm heat syndrome,Blood stasis syndrome,Qi stasis syndrome,fluid retention syndrome as self variable,and using Binary logistic regression analysis (Enter).The results showed that the coefficient of Phlegm heat syndrome is 1.392,the relative risk is 4.024, relative risk with 95% confidence interval is 1.146～14.122.Conclusion1.The pathological basis of non-valvular atrial fibrillation was Qi deficiency syndrome and Blood stasis syndrome.The most common combination syndrome of non-valvular atrial fibrillation was the combination of syndromes of the Qi deficiency syndrome and blood stasis.2.The pathological viscera of non-valvular atrial fibrillation was mainly the heart and closely related to the spleen and the kidney.3.Phlegm heat syndrome for non-valvular atrial fibrillation with coronary heart disease was the specific syndrome.