Investigation On The Economic Burden Of Three Major Bacterial Meningitis Cases In Some Areas

BackgroundBacterial Meningitis (BM), also called purulent meningitis in the past, is a class of bacterial meningitis infection or meninges caused severe central nervous system infection. The disease with fever, headache, vomiting, irritability and other symptoms as the main performance. Nervous system and cerebrospinal fluid abnormalities. Because the disease can cause substantial damage meningeal adhesion and brain, it can appear cranial nerve palsy, blindness, hearing impairment, paralysis, epilepsy and mental deterioration sequelae. China CDC since 2006 to carry out population-based acute encephalitis meningitis surveillance and laboratory testing, has in Jinan City, Shandong Province, Yichang City, Hubei Province, Shijiazhuang City, Hebei Province, Guigang City, Guangxi Zhuang Autonomous Region and Baoji City,Shaanxi Province conducted sentinel surveillance. By improving the monitoring capacity, access to cases of morbidity and mortality and other data and information to determine the epidemiological burden of disease incidence and mortality and other related diseases. Vaccines as a public health interventions, formulate its immunization strategy depends on the epidemiology of the disease burden of illness, economic burden, vaccine availability, effectiveness and safety and other factors, the economic burden is an important part of. In recent years, China has reported Nm due to the epidemiological burden of bacterial meningitis, but few reports on the financial burden, the burden of disease data Sp and meningitis caused by Hib rarely reported, for carry out this study, understand Nm, Sp and economic burden caused by Hib bacterial meningitis disease.ObjectUnderstand the study area by Neisseria meningitidis (N. Meningitidis, Nm), Streptococcus pneumoniae (Streptococcus Pneumonriae, Sp) and Haemophilus influenzae type b (Haemophilus Influenza Type b, Hib) caused by three kinds of bacterial pathogens meningitis disease burden, providing data support and advice for the development of the local immunization program policy and for the development of bacterial meningitis in the country the burden of disease research and exploration methods.MethodsDescripted epidemiological method was done using the data from the Acute Encephalitis and Meningitis System during 2006-2014(Sep 1,2006-Dec 31,2014), the epidemiological burden of bacterial meningitis caused by all, and is caused by Nm, Sp and Hib the economic burden of bacterial meningitis.ResultsDuring 2006-2014(Sep 1,2006-Dec 31,2014), Jinan City, Shandong Province, Yichang City, Hubei Province and Shijiazhuang City, Hebei Province, three bacterial meningitis cases per direct economic cost of the Nm, Sp caused and Hib was 48,932.05 yuan per cases indirect economic cost of 10,491.46 yuan per cases total economic cost of 59,423.51 yuan. The Nm, Sp and Hib bacterial meningitis sequelae caused by the type of occurrence the top three followed by unconsciousness, slow language nerve deafness (or deaf children), quadriplegia and cerebral infarction.conclusionBacterial meningitis economic burden of disease severity. It proposed to continue to strengthen the monitoring of bacterial meningitis, and based on the results of this study, combined with the application of new vaccines, appropriate to carry out the evaluation of health economics.