Anterior Cingulate Gyrus And Orbital Frontal Cortex Involved In The Risk Of Different Decision-making Process

Risky decision making is to decide under the condition where the outcome of each choice is defined by a certain probability that follows. At present, Researches about the neural mechanisms of risk decision received widespread attention. Probability discounting task is one of the classic paradigm of risk decision making research, in order to investigate the impact of reward probability on rat’s behavior. In present research, we use the multi-channel synchronous recording technology to observe and record neuron signals of rat’s anterior cingulate cortex (ACC) and orbital frontal cortex (OFC) during probability discounting task. Analyze the relationship between the neuron signal’s features in the two regions and rat’s behavior. Then we can investigate the specific role of ACC and OFC play in risk decision making, and furthermore, the relationship of this two regions during risk decision making. In this study, we found that,(1) After learned the task, the rats can adjust their behavior in order to gain more reward.(2) Three kind of neurons have been recorded in this research, these neurons involve in important stages of predict, action and reward in risk decision respectively.(3) There different kinds of neurons in ACC encoding the information about number of reward, uncertain and probability. However, the neurons in OFC are insensitive to the probability information.