Preparation Of Amphiphilic Polymer Nanoparticles On The Basis Of Sulfobetaine

Polybetaine is natural materials for antifouling coatings which is promising tobe an alternative material to the toxic antifouling coatings. Phase separation occursonce polybetaine is dispersed in the organic matrix because its nature of highpolarity of zwitterionic groups, which may reduce the mechanical properties ofcoatings and shorten the life of paintings and further dramatically limit theirapplication in marine antifouling coatings. Polymer nanoparticles containing thestructure of inner betaine and outer hydrophobic shell are promising to solve thisproblem. To achieve this goal, the macroinitiator with different molecular weightwas first prepared from N-butyl methacrylate (BMA), methyl methacrylate (MMA)and butyl acrylate (BA) by atom transfer radical polymerization (ATRP) in thispaper. Then, the polymerization of2-(Dimethylamino) ethyl methacrylate(DMAEMA) was carried out using macroinitiator to prepare amphiphilic blockcopolymers. Finally, nanoparticles of polybetaine with hydrophobic shell andhydrophilic core were synthesized by the reaction between amine in the blockcopolymer and1,3-propane sultone in chloroform. Then, the structure ofnanoparticles was changed to obtain the micelles with hydrophilic shell andhydrophobic core by changing the solvent to deuterated water.