Preparation Of Core-shell Silver-molecularly Imprinted Polymers And Study On SERS Performance

Surface-enhanced Raman scattering (SERS) technique has attracted considerableattention in recent years due to its nondestructive and highly sensitive characterizationfeatures. SERS is highly dependent on the SERS-active substrate, especially their sur-face nanostructures. The present study shows that Au, Ag and Cu are most researched inall SERS-active substrate materials, and the enhancement effect of Ag is best. Unfortu-nately, some of the conventional SERS-active substrates are highly reactive and unsta-ble, resulted the reduction or loss of SERS signals. Furthermore, the classicSERS-active substrate is nonspecificity, vulnerable to the interference of impurity ele-ments, influencing the sensitivity and accuracy of the test results. Further explorationand construction of core-shell silver-molecularly imprinted polymers (Ag@MIPs)SERS active substrate may open up a new avenue of SERS technique.We study the preparation plan of flower-like Ag, spherical Ag and cubic Ag to seekthe optimal preparation conditions, also conducting a series of structure characterizationand SERS performance study for the obtained particles. Results showed that: these goodmorphology particles are pure Ag particles. The SERS effect of flower-like Ag andspherical Ag is stronger than cubic Ag, the detection limit of which are10-6mol/L、10-8mol/L、10-7mol/L respectively.We study the preparation of Ag@MIPs, also conducting a series of structure char-acterization and SERS performance study for them. Use the flower-like Ag and spheri-cal Ag as core respectively, and Use Rh6G as imprinting molecule to prepare theAg@MIPs. Results showed that: spherical Ag1surface evenly coated with a16nmthick molecularly imprinted polymers layer. The detection limit of this Ag@MIPs parti-cles is10-16mol/L. Furthermore, its specific recognition ability is superior to the con-ventional SERS-active Ag substrates, realizing the specific identification and ultrasensi-tive detection for the specific molecular Rh6G.