Functionalization Of Graphene Preparation And Evaluation Of Composite Materials

[Objectives]In this essay, we researched a magnetic modifications of the function after the application of the graphene oxide carrying drugs, And to study its biological security by MTT Method; And then, We prepare silver nanoparticles/polyethyleneimine (PEI)-reduction graphene oxide (AgNP/rGO-PEI) composite materials and odium naphthalene sulfonate(NA)/reduction grapheme oxide-Silver nanoparticles (AgNP/rGO-NA) composite materials, And analyzed their stability, antibacterial activity, cellular toxicity.[Methods]Firstly, prepare sodium naphthalene sulfonate(NA)/grapheme oxide-Fe3O4(Fe3O4GO-NA) composite materials, and evaluate their quality performance. Sodium naphthalene sulfonate grapheme oxide-Fe3O4which was shortened as Fe3O4GO-NA were prepared and then their magnetic performance, Drug carrying property Sustained release performance and cellular toxicity were analyzed.Secondly, prepare silver nanoparticles/polyethyleneimine (PEI)-reduction graphene oxide (AgNP/rGO-PEI) composite materials, and evaluate their quality performance.Firstly prepare AgNP/rGO-PEI, and then through the nanoparticles modified with polyvinylpyrrolidone silver (PVP/AgNP) Comparative analysis of its stability, antibacterial activity, cellular toxicity.Finally, prepare sodium naphthalene sulfonate(NA)/reduction grapheme oxide-Silver nanoparticles (AgNP/rGO-NA) composite materials, and evaluate their quality performance. Sodium naphthalene sulfonate reduced grapheme oxide-silver nanoparticles which was shortened as AgNP/rGO-NA were prepared and then their stability, antibacterial activity and cellular toxicity were analyzed.[Results]The study found The prepared Fe3O4/GO-NA can be considered as superparamagnetism, and magnetization saturation reaches16.4emu/g. The loading rate of Fe3O4/GO-NA to DOX is58.63%;0.05g of graphene oxide drug carrying capacity is1.182mg; Fe3O4/GO-NA having a more excellent Sustained release performance, and relatively low biological toxicity. Fe3O4/GO-NA composite materials has reliable quality, good performance.The study found AgNP relatively uniform distribution in AgNP/rGO-PEI surface, silver nanoparticles mass fraction is4.5%, a particle size is6-13nm, zeta potential of-47.9mV; under in dark or light intensity3000LX Low illumination meter environment (lux) for10days, PVP/AgNP aggregation is more obvious, and the AgNP/rGO-PEI good dispersibility, aggregation is not obvious; AgNP/rGO-PEI having a more excellent antibacterial activity, biological compatibility and relatively low biological toxicity.The study found AgNP relatively uniform distribution in AgNP/rGO-NA surface, silver nanoparticles mass fraction is4.3%, a particle size is5-15nm, zeta potential of-42.3mV; Antibacterial rate of AgNP/rGO-NA after6h of exposure with E.coli and S. aureus were98.6%,98.9%. having a more excellent biological compatibility and relatively low biological toxicity.[Conclusions]After a good surface modification of graphene-based composite materials not only have their own excellent properties of graphene,Such as great specific surface area, high optical absorption, high strength; But also to obtain more excellent performance, can be good performance for the preparation of drug carriers such as Fe3O4composite graphene-based drug carrier, can capable of producing more excellent antibacterial properties of composite materials such as graphene-based nano-silver antibacterial composite material used. Therefore, graphene-based composite materials in various fields in the world today have a very broad prospects for development and application of space.