Studies On Selenium(0)-insertion Reactions Of Arylboronic Acids

Selenium ethers compounds are important intermediates, chiralligands and functionals, while they also have the biochemical andpharmacological effects. Selenium ethers compound is one kind of thehot research topics in organic chemistry, medicinal chemistry andmaterials. This thesis will be focused on arylboronic acid involved withselenium insertion reaction, and divided into four chapters.Chapter one, recent advances in the synthesis of diaryl diselenide,diaryl selenide has been reviewed.Chapter two, in the presence of N-bromosuccinimide, weinvestigated metal free promoted arylboronic acid react with elementalselenium to construct symmetrical diaryl diselenide. We also studied thepreliminary reaction mechanism. The important features of thismethodology are broad substrates scope, simple operation, high yielding.Chapter three, there has been developed CuCl/Bathophenanthrolinecatalyed arylboronic acid react with elemental selenium to synthesissymmetrical diaryl selenide. The important features of this methodologyare simple operation, reaction mild. We provide a new route to synthesissymmetrical diaryl selenide. Chapter four, the typical experimental procedures, spectra data ofthe corresponding products was described.