Design Of Multi-functional Heparin Workshop

Heparin product is the most important kind of antithrombotic drug, takes up huge market shares, and the market demand is on the rise.This subject is the design of heparin API workshop where includes two production lines, manufacturing three kinds of drug substances:Heparin sodium, Heparin calcium, Nadroparin calcium.This design includes characteristic and principle instruction for manufacturing process, manufacturing process designation, material balance during manufacturing process, selecting and calculation for equipment, designation for workshop layout, environment protecting and safety production, GMP certification and others. And the designation achievement includes list for production equipments, manufacturing process flowchart, layout chart for the workshop.The innovations for this designation:the workshop designed can meet the requirement that manufacturing three kinds of drug substances-Heparin Sodium, Heparin calcium, Nadroparin Calcium. This designation dissolves the problems that single product, low utilization rate for clean area, high fixed cost and Heparin sodium is designed as the starting material for Nadroparin Calcium which can shorten the delivery period for the drug substance.The workshop designed is useful, and the drug substances manufactured has low fixed cost and low management cost for the type of materials used for different kinds of drug substance is same.