Studies On Silver Catalyzed Decarboxylative Nitration And Palladium Catalyzed Decarboxylative Hiyama Coupling Reaction Of Aromatic Carboxylic Acids

Carboxylic acids are cheap and readily available, easy to store compounds. Recently，the transition metal-catalyzed decarboxylative/oxidative cross-coupling reactions withcarboxylic acids have been extensively studied.The main goal of our research is toachieve some novel catalytic decarboxylative/oxidative coupling reactionsby the use oftransition metal catalyst.Chapter1briefly describes the research progress on decarboxylative/oxidativecoupling reaction, and proposed research this article.Chapter2describes the progress in the synthesis of aromatic nitro compounds. Wedeveloped silver catalyzed decarboxylative nitration using sodium nitrite as nitrationreagent. This new method not only provides a new path for the synthesis of aromaticnitro compounds, but also expands the concept of thedecarboxylative/oxidativecarbon-hetero coupling reaction.Chapter3introduces the palladium-catalyzed decarboxylative Hiyama couplingreaction. Using this method，we achieved the decarboxylative/oxidative coupling of arylcarboxylic acids and aryl silicon reagent. This method not only increases the substraterange of Hiyama reaction, but also provides a new route for the synthesis of diarylcompounds.In summary, this paper mainly focus on the use of silver and palladium as the catalystto achieve the decarboxylative nitration reaction and decarboxylative Hiyama couplingreaction，respectively.