Synthesis And Biological Activity Of New Insecticides And Chlorantraniliprole Derivatives

The new neonicotinoid insecticide thiacloprid is an insecticide by the German andJapanese Joint development of sucking and chewing insects is very effective, it is thenervous system by blocking conduction to kill pests, thiophene thiacloprid followingstructure:NCNNCThis paper describes the development prospects of novel nicotinic compounds, Andthe shortage dimethyl cysteamine hydrochloride thiazolidinedione, through thiazolidinewas reacted with a halogenated synthetic products and by changing the chlorides andthiazolidine, two series of synthetic compounds, and by detecting the biological activityof new compounds to screen new varieties of pesticides.This paper is mainly done neonicotinoid insecticides, in addition to the synthesis of aseries of Chlorantraniliprole derivatives,A series of p-chlorophenyl hydrazineethoxymethylene cyanoacetate and synthetic amino acids, saponification and acidchloride synthesized Kang width macrocycle ring-opening synthesis of the final product,as a starting material with another series of thio glycolic acid, the reaction of the esterwith methanol and then with a2-chloro-3-cyano pyridine ring, saponification, andKang wide chloride, ring opening to give the final product， Chlorantraniliprole researchhotspot in recent years, so we benzoyl chloride insects amide transformation, two seriesof compounds are synthesized, the structure of the formula:...