Synthesis And Performance Of Several Energetic Pyridine-based Compounds

Nitropyridine energetic compounds, often have high nitrogen, enthalpy of formation, and low sensitivity, good thermal stability because of the existence of nitrogen heterocyclic ring and polynitro groups. These compounds have good application prospect in the field of insensitive high explosives and insensitive propellants.Several pyridine energetic compounds have been designed and synthesized, and the preliminary performance research of these compounds have been carried on.(1) 2-Chloro-4-amino-3,5-dinitropyridine and 2-amino-3,5-dinitro-6-chloro-pyridine we-re obtained by nitration of two raw materials 2-chloro-4-amino-pyridine and 2-amino-3-nitro-6-chloro-pyridine, followed by condensation with 5-aminotetrazole under alkaline conditi-ons, to give two novel (5-amino-tetrazol-1-yl) substituted pyridine energetic compounds 2-(5-amino-tetrazol-1-yl)-4-amino-3,5-dinitro-pyridine and 6-(5-amino-tetrazol-1-yl)-2-amino-3,5-dinitro-pyridine. A preliminary research on the detonation properties and thermal behavior of the two compounds were then carried on.(2) A novel energetic compound 6-(4-nitro-imidazol-1-yl)-2-amino-3,5-dinitropyridine and an energetic intermediate 6-chloro-3-nitro-(4-nitro-imidazol-1-yl)-pyridine were obtained by condensation of two raw materials 2-amino-3,5-dinitro-6-chloro-pyridine and 2,6-dichloro-3-nitro-pyridine with 4-nitro-lH-imidazole respectively under alkaline conditions. N2-(dinitrotetrazolo[1,5-a]pyridin-5-yl)-2,6-diamine-3,5-dinitropyridine was obtained by co-ndensation of itself. A preliminary research on the detonation properties and thermal behavior of 6-(4-nitro-imidazol-1-yl)-2-amino-3,5-dinitropyridine were then carried on.(3) 2,6-dichloro-pyridine was used as a raw material, followed by nitration, animation, reduction, cyclization and methylamination, to give a novel pyridincyclourea nitro-amine intermediate 5-methylamino-6-nitro-1,3-dihydro-imidazo[4,5-b]pyridine-2-one. Effects of different reaction conditions on yield of the nitration, reduction, cyclization reactions were studied.All the synthesized compounds were characterized by means of 1H NMR,13NMR, IR, MS et al.