The Thiolation Research On Azide Compounds And Graphene Oxide

Be considered as precursor of graphene, graphene oxide has attracted interests in abroad researches due to its unique two dimension structure and novel properties in mechanical, optical, chemical functionalization and electronic. Surface modification on graphene oxide will extend the species and applications of graphene derivatives. Thiolation of graphene oxide has been application on loading nanoparticles and surface modification, however, current researches on graphene oxide thiolation are rare. Organic azides are active compounds which always be applied in fine chemical industry and biotechnologies. 1,3-dipolar cycloaddition between azide and alkyne has extensive applications in surface modification and dendrimers synthesis. Azide thiol has applications in the functionalization on substrates surface and nanoparticles, which is becoming hotspot in surface modification field.With the research on thiolation as the mainstay, we utilized the sulfide reagents for thiolation of organic azides and graphene oxide. Additional, we also explore the effects of solvents and surface groups on graphene derivatives impedance with the microfluidic chip designed and manufactured in our laboratory.In the first place, introduction of properties and application of azide and graphene oxide are depicted, furthermore, we also illustrate the research significance and main contents of thesis. In the second place, two thiolation reagents are utilized to synthesize azide thiols. Potassium thioacetate will cause problems such as complex operation and harsh conditions. However, thiourea, as a green chemistry reagent, can be utilized to optimize the reaction conditions. The results indicate that the operation is easier and reaction conditions are also mild.In the third place, we propose a new proposal to generate thiol modified graphene oxide with thiourea for the first time, and we get good results according to the characterizations. We also obtain conclusions about the mechanism by controlling the amount of reactants, it has approved that the reaction sequence of the functional groups in the reaction between graphene oxide and reagents, that is, hydroxyl group is easier to react with thiourea than epoxy, which provided strong evidence for reaction mechanisms on graphene oxide.At last, a groundbreaking research on the impedance of the graphene oxide solution is implemented and the feasibility of the experiment is discussed. We utilize microfluidic chip which is designed and manufactured in our laboratory.to measure impedance. Pure water,50% ethanol and ethanol are utilized to prepare solutions to explore the effects of solvents on impedance of graphene oxide. In addition, we also explore the effect of surface groups on graphene derivatives impedance with three samples, which could indirectly reflect the difference of the groups on samples.