Hydrothermal Synthesis Of Some Low Toxic Doped-quantum Dots And Their Application In Analytical Chemistry

Nowadays, the research and technical exploiture of Doped-quantum dots(D-QDs) is one of the most interesting fields in nano-technology. The focus researches are the preparation and application of Doped-quantum dots with stability, excellent biocompatibility and powerful multifunction. In the dissertation, the authors mainly studied on the synthesis and application of new functionalized quantum dots. The dissertation includes four chapters, the main contents and results are summarized as follows:Chapter one, the basic conception and physical property of doped-quantum dots were introduced. The authors reviewed the recent progress about the synthesis, surface modification and application, and then put forward the research goal of this dissertation.Chapter two, core-shell and water-soluble Zn S:Mn@Zn S:Cu QDs was synthesisized by hydrothermal method using 3-Mercaptopropionic acid(MPA) as a stabilizer. p H, reflux time,reaction temperature, even atmosphere were investigated. The characterizations of Zn S:Mn@Zn S:Cu QDs were also identified using STM, IR, powder XRD and thermogravimetric analysis. For an excellent fluorescence and phosphorescence of Zn S:Mn@Zn S:Cu QDs, the optimal conditions were p H 11, reflux temperature 80 0C and reflux time 4 h under N2 atmosphere.Chapter three, water-soluble functionalized Cu In S2@Zn S core-shell quantum dots were synthesized with MPA as the stabilizer. It was developed for the sensitive and selective detection of trace mercury ions with Cu In S2@Zn S core-shell quantum dots as fluorescence probes. Influence factors, including the concentration and p H of buffer, and quantum dots concentration, were investigated. Under the optimum conditions, a good linearity was obtained between P0/P and the concentration of mercury ions(C) in the range from 6.0×10-8~1.0×10-5 mol/L with the correlative coefficient of 0.9923 and a limit detection of 3.56×10-9 mol/L The proposed method has been successfully applied to detect the content of mercury ions in water samples, the recoveries were found to be 92.5~105.9% with standard addition method.Chapter four, water-soluble Ag In S2:Mn and Ag In S2:Mn@Zn S QDs have been synthesized in the presence of d BSA as capping ligand. Trypsin can digest BSA and remove BSA from the surface of Ag In S2:Mn@Zn S QDs, thus quenching the fluorescence and phosphorescence of QDs. A new approach was developed for the sensitive and selective detection of trace trypsin with Ag In S2:Mn@Zn S QDs as fluorescence and phosphorescence probes...