The Activation Of Aromatic Nucleophilic Substitution And Addition Reactions

The present text is based on the the large quantity cultural heritage report for the reaction between m-dinitrobenzene ramification and nucleophilic reagent. There are three different nucleophilic reagent respectively reaction with m-dinitrobenzene ramification at distint alkaline term:With the nitrobenzene , m-nirtobenzenesulfone sodium salt , 2.4-dinitro chlorobenzene , m-dinitrobenzene for bottom thing, benzyl cyanide, benzyl chloride, benzyl chloropyridine,is a nucleophilic reagent reaction for under the different term proceeds a series reaction. At the same time ,discuss about the impact factor to nucleophilicity such as the number of attract electron group, ability of attract electron and the nucleophilic substitution reaction part.With the nitrobenzene, m-chloronitrobenzene, m-nirtobenzenesulfone sodium salt for bottom thing, Grinard agent is a nucleophilic reagent reaction for under the different term proceeds a series reaction.With the m-dinitrobenzene , 2.4-dinitrochlorobenzene for bottom thing, Mandelonitrile is a nucleophilic reagent reaction for under the different term proceeds a series reaction.There are impact factor to be discussed such as solvent polarity, nucleofuge, attract electron group the nunucleophilicity of nucleophilic reagent.According to the ~1H-NMR ,~13C-NMR ,IR spectrum, chemical element analyze the right production thing the proceeding the construction to determined,at the same time disscused about the reactivity of m-dinitrobenzene ramification.