Polymer-supported Cinchona Alkaloid Catalyst Synthesis Of Research

In this thesis, cinchonidine was modified by measures of chemistry, and different synthesis methods of polymer-supported cinchona alkaloids were studied. In addition, homopolymer of cinchonidine and diblock copolymer were synthesized by using Reversible Addition Fragmentation chain Transfer technique (RAFT). Finally, N-(Diphenylmethylene) glycine tert-butyl ester which was used as a substrate was synthesized. This thesis consists of three parts:1. The synthesis of dendronized polymer (or dendrimer)-supportedcinchona alkaloidsChiral phase-transfer catalyst 3 (N-(9-Anthracenylmethyl) cinchonidinium bromide) was synthesized from cinchonidine and 9-hydroxymethylan thracene, andmodified by using different anhydride.'The factors that affected the reaction, such as temperature, solvent were investigated.2. The synthesis of diblock copolymerHomopolymers of cinchonidine and copolymers of cinchonidine with NIPAM were synthesized by using Reversible Addition Fragmentation chain Transfer...