A Associstion Study Between Dyslipidemia And Diet Among Yugur Population From Gansu Province

OBJECTIVES:Through the epidemiology investigation and laboratory testing to get the information of the dietary pattern, the physical examination and the levels of blood lipids and blood pressure about the residents of Yugur regions in Gansu Province, to study and analyze the relevance between these factors and the dyslipidemia, to know the distributed situation of the dyslipidemia and the risk factors of the diet among the residents of Yugur regions on northwest of China, and to provide the early theoretical basis for the prevention, the diagnosis and the treatment of those relative diseases. Thus, it can achieve the purpose of preventing and curing diseases by the intervention of dietary pattern.METHODS:The method of cohort stratified random sampling was adopted to investigate the diet habit and lifestyle of those residents who are Yugur nationalities, lived in the Yugur Autonomous County of Gansu Province and the age over 18 years. The medical inspection were execute to measure the body height, body weight, abdominal circumference, blood pressure and other health indictors of those residents. The level of TC, TG, LDL-C and HDL-C of plasma were tested. The statistical method of single factor and multiple logistic regressions were used to analyze those data above. The analysis focused on the correlation between the diet habit and the dyslipidemia.RESULTS:(1) High TG and high LDL-C were the main types of hyperlipidemia for the location residents. The abnormal rates were 45.66% and 13.04% respectively. The dyslipidemia related with age and gender. The total rate of dyslipidemia among males was obviously higher than among females (P<0.01), the incidence of high TC, high TG and high DL-C increased with age, it would reach the peak level in the age of 55～64 years old. The incidence of TG and LDL-C among those females whose age were over 65 years old was obviously higher than among males (P<0.05). (3) The incidence of high TC and high LDL-C among Yugur were significantly higher than Han and Tibetan (P<0.01, P<0.05), the high incidence for TG among the Han and Tibetan was significantly higher than among Yugur (P <0.01). (4) A statistical difference of the level for TC and LDL-C was observed between the hypertension group and the control group(P<0.01, P<0.05), the levels of TC, TG and LDL-C among overweight group and obese group were higher than among normal weight group(P< 0.05). (5) The foods were generally high-calorie for those location residents. The single-factor variance analysis showed us that the amount of foods intake of the beef, mutton, animal offal, butter, wine and tobacco were higher among those people who were dyslipidemia than among the normal population. The multi-factor Logistic Analysis showed us that the beef, mutton, wine, animal offal and the butter were risk factors of high blood cholesterol of Yugur population among those factors that were involved in the is regression model (OR values were 1.252,1.306,1.985,1.33 respectively).CONCLUTIONS:A remarkable correlation was observed between the dyslipidemia and the overweight, obesity, abdominal obesity and the high blood pressure. There was a close relationship between the dietary factors and the lipid abnormalities for those location residents. An effective dietary intervention measure should be taken to prevent the occurrence of high blood cholesterol and the followed impact.