| ObjectiveResearch on epidemiology features and TCM syndrome characteristics of ulcerative colitis (UC) aims to learn different stages of disease, TCM syndrome of illness degrees, lung function injury, performance of colonoscopy microscopically and the correlation among them.It will verify and enrich Chinese medicine theory to guide clinical diagnosis and treatment.MethordThe UC patients, without respiratory system disease, were selected between September 2009 and March 2011.They were chosen from Beijing DongZhiMen Hospital, China-Japanese Friendship Hospital, XiYuan Hospital, Shanghai LongHua hospital, First affiliated Hospital of Henan Chinese medicine college, Jiangsu general Hospital and Shenyang Military Hospital.Besides, we collect general information, symptoms, tongue and pulse manifestation, blood test, lung function, colonoscopy and histopathology,etc. from another finished'973' study.ResultsEpidemiological survey covered 261 people (lung function include 199 people, colonoscopy take 197 people, correlative investigation of the three bring about 171 people in) including 143 males and 118 females. Meanwhile, high-risk groups occurred among patients aged 18-70 or 31-40, Body Mass Index (BMI) between 15.12 and 38.63,cultural degree in university.UC are frequently seen in active period,chronic recurrent type,and slightly disease degree aggravated with diet disturbances,overwork,and so on. Disease extent in rectosigmoid and the sigmoid colon, total colon incidence nor low,.Oral recurrent ulcers, fatty liver, neurodermatitis respectively were the top three parenteral performance.58.62% UC patients appeared chest symptoms, such as shortness of breath, cough, bosom frowsty. Different condition (light, medium, heavy) had a remarkable difference (P< 0.05) with TCM symptoms integral, clinical activity index, endoscopic index, colonoscopy grading, lung function injury, the platelet count in different stages of activity and remission period. In correlation, TCM syndrome distribution and colonoscopy microscopically injury and lung function are statistically significant (P< 0.05). Lung function and colonoscopy damage has no obvious statistically significant relationship (P> 0.05).ConclutionIn the cases, male's and young and middle-aged people's UC morbidity are higher compared with female's. BMI mostly in the normal range. People who received higher education, living in big cities, concurrently undering overwork, bad mood and improper food are more tend to concer UC. More patients had longer duration of symptoms on clinical activity or chronic recurrent type.With mild-to-moderate primarily, parenteral performance and rectosigmoid lesions were seen most. Most patients manifested chest symptoms and different degree of lung function injury, relating to the activity and pathological. In syndrome and colonoscopy performance, DaChangShiRe type exudate obvious and were damaged heavily, while bowel mucosa of XueYuChangLuo type become fragile apparent, DaChangShiRe type in TCM syndrome distribution showed more limited lung function abnormal. PiQiKuiXu and XueYuChangLuo type often takes on decreasing diffuse changes.Lung function and colonoscopy damage has no obvious statistically significant relationship. |