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Clinical Studies Of The Impact Of Portal Hemodynamics And Liver Function Of Liver Cancer Chemoembolization

Posted on:2002-01-22Degree:MasterType:Thesis
Country:ChinaCandidate:J L ZhangFull Text:PDF
GTID:2204360032956147Subject:General surgery
Abstract/Summary:PDF Full Text Request
To study the effects of hepatic arterial chemoembolization on portal hemodynamic and functional reserve in patients with primary liver cancer, this research adopts mainly Color Doppler Flow Imaging (CDFI) and CT scan technology, in order to make the comparative observation of hemodynamics and functional reserve changes before and after chemoembolization in 17 patients. The results revealed: ①the average PVF and SVF gradually were reached their peaks at 1 week after embolization, then they gradually decreased to the normal level in 6 weeks after HACE, but the diameter of portal vein and splenic vein was not changed significantly; ② the Congestion Index (CI) of portal vein was not changed remarkably (P>0.05) before and after embolization; ③ the Parenchymal Hepatic Embolization Ratio (PHER) was between 10.63%~43.83% (average 26.31%), 2 cases over 40%. If the PHER below to 40%, the Hepatic Function Reserve (HFR) could be compensated for the need of liver function. We conclude the analyses of portal venous hemodynamics could provide an important index for the prognoses of HACE,it also could help us to decide further treatment. The CI could help us to analyses the change of portal venous pressure. From the analyses of PHER, we could calculate influence of HACE on HFR, it would help us to evaluate HFR.
Keywords/Search Tags:Hepatocellular Carcinoma(HCC), Chemoembolization, Hemodynamics, portal vein, Hepatic Function Reserve, Color Doppler Flow Imaging, Congestion Index, Parenchymal Hepatic Embolization Ratio
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