| Being a connective tissue disease, Scleroderma has the characteristics of spectrum. Some severe cases can lead to multi-systemic and multi-organnic damage, which directly threaten the life quality of the patients or even deprive them of their lives. Because of its unclear pathogeny, the treatment for Scleroderma is very difficult and no effective drugs that can cure the disease are available at present. But both TCM and western medicine have acquired certain achievements with the development of research. The related literatrure on the pathogeny of the disease in recent years are collected to provide the newest references for further treatment and the problems and tendency of its study are analyzed. The development of reseach in pathogeny and therapy of TCM and western medicine is disccused emphatically in the first part of paper and the therapeutic experience of professor Ai are offered in the second part. |