Forefront Of The Urinary Suppository In The Treatment Of Chronic Nonbacterial Prostatitis (damp-heat Stasis) Randomized Controlled Clinical Trials

Chronic Prostatitis (CP), a commonly encountered disease of male adult, is a clinical syndromes with the main effect of dysuric symptom and bladder genital area pain. The number of the patients who have the above syndrome is about 33% of all patients in andrology clinical service, and 90%～95%is chronic pelvic pain syndrome (CPPS).The pathogenesy of CPPS is not clear,and is consided to be related to factors of infestation of pathogenic microorganism,urine backstreaming,autoimmune response,disorder function of pelvic cavityautonomic nerve ,and psychologic factor.The influence of CCPP to the quality of life is severitily, and the treatment effectiveness is not satisfied.CP belongs to the scope of JINGZHUO in the field of TCM. It locates in the JINGSHI, which is related to the kidney and bladder as well as to the liver, lung, spleen, heart and SANJIAO. Its mechanism character is: humid hea,stagnant blood,renal deficiency.The main TCM pattern of syndromeis damp invasion of lower energizer combine with qi-stagnancy and blood stasis.There are definite advantages and effectiveness in treating CP with TCM, and the method of per rectum, which can improve the syndromes and get satisfactory effectiveness, also be utilised popularly.The observation is strictly accorded to the Guideline Principle of Clinical Research on New Drug of Traditional Chinese Medicine and the requirement of clinical epidemiology,.In order to observe the effectiveness and adverse reaction of QIANLIEMINIAOSHUAN to CPPS, the clinical trial adopts random, double-blind and controlled method,and make the QIANLIEANSHUAN as control drug.,The changing rate of TCM symptom score and NIH-CPSI score is used to evaluate the comprehensive effect. The 48 cases are involved during this period of the trial, and among them the 24 cases are in testing group, 24 cases are in control group. There is no significant difference between the 2 groups in the age, weight, height, ill period and type of disease distribution, so it is of comparative. The clinical curative effect shows as follow: After 4 weeks treatment, the effective rate of the testing group is 58.33%, the control group 20.83%. There are all significant differences between the two groups. The testing group is more advanced than the control group. QIANLIEMINIAOSHUAN can significantly reduce t TCM symptom score and NIH-CPSI score,and is more advanced than the control group(P<0.05)。There is no difference between variance rationg of the 2 groups in WBC and lecithin of EPS(P<0.05),There is not any adverse reaction. Analysing the effectiveness of the observation, we an found that QIANLIEMINIAOSHUAN can relief the severity degree and improve largely the...