Huoxuezhitong Capsule Secondary Research And Development

Huoxuezhitong Capsules are used to treat Soft tissue injury, pain and distention made by stasis. The prescription is made up of Angelica, Eupolyphaga seu stelcophaga, Boswelliacarter, Radix Notoginseng, Borneolumsyntheticum, Pyritum.Modern and advanced technology and method were used in the article to study on the Huoxuezhitong Capsules, and to make a new development, in order to raise the technical content and compete power of products, and the curative effects. The preparation technology and quality standard were studied in the article.SFE-CO₂, β-cyclodextrin inclusion and mini-grinding technologies were used in the article. The study was carried out with orthogonal design and single factor design, and given consideration to the actual situation of produce to optimize the best extract method and optimum inclusion process. The truce angle was used as evaluating indicator to select the optimum preparation process, and CRH, which has been determined, would be an important parameter in the actual situation of produce.Increasing Boswelliacarter qualitatively tested by TLC, Borneolumsyntheticum was qualitatively tested by GC, Ferulic acid were quantitatively analyzed by HPLC on the basis of the original quality standard. Methodology check is founded. New quality standard has predigested pretreatment of specimen, is stable and trusty, is an biggish improvement. The results of accelerated testing indicated the new technologic productions are steady.The new technological process was based on the pharmacodvnamics, and combined with reports of literature. The results of primary pharmacodynamics show that, new technological products were better than original technological products on the aspect of anti-inflammation,...