Gloomy Particle Treatment Of Depression Model Rats Pharmacodynamics

Research PurposeBy means of experimentation and observation, study the effect of AMD granule on depressing the action of rat and intracerebral monoamine neurotransmitter,and preliminarily study its. Research SignificanceThis experimentation is aim to observe action procedure AMD granule acted on mental depression symptom to study its mechanism of action and do service for efficient and low-toxin new products as basis.There are lots of compound Chinese traditional medicine can effectively develop clinical representation of mental depression symptom in the field of Chinese.lt will have great operation significance if it can be explored systematacially and effectively. Research ResultBy observing rats' action in one model set,the following clinical representation accord with the pathogenesis of mental depression symptom:horizontal and vertical action decrease,sugar water consumption lessens,the content of monoamine neurotransmitter declines.Compared with model set,the highdose set of AMD granule represents different result:it can develop the action of rats in depression model set, increase the horizontal and vertical acion times and contents of intracerebral monoamine neurotransmitter. Compared highdose of Chinese traditional medicine set with western medicine set, it is not obvious difference on the consumption of sugar water as well as horizontal and vertical action.The comparation has statistic significance for the efficacy of NE. ConclusionThis task discussed antidepressant efficacy and mechanism of action of AMD granule.It is obvious that AMD granule that AMD granule exactly develop the rats' action in depression model set and contents of monoamine neyrotransmitter upon this experimentation,it is also supply primary experimental data to cure mental depression symptom by Chinese traditional medicine.